Results 61 to 70 of about 77,813 (254)

Midgut-derived NPF controls mating-induced GSC proliferation.

, 2018
A model illustrating the mechanism based on this study. SP signaling induces NPF release from midgut EECs. NPF positively controls pMad expression in GSCs to induce GSC proliferation via ovarian NPFR. BMP, bone morphogenetic protein; EEC, enteroendocrine
Shu Kondo (769011), Ryusuke Niwa (141031), Michael J. Texada (746481), Yuto Yoshinari (5782886), Tomotsune Ameku (2839499), Yuko Shimada-Niwa (835526), Kotaro Amezawa (5782889), Goro Yoshizaki (5782892)   +7 more
core   +1 more source

Exploring the midgut physiology of the non-haematophagous mosquito Toxorhynchites theobaldi

Open Biology
Toxorhynchites mosquitoes have an exclusively phytophagous feeding habit as adults, which leads to significant differences in their morphophysiology compared with haematophagous mosquitoes.
Renata C. Barbosa, Raquel S. M. Godoy, Priscila G. Ferreira, Tiago A. O. Mendes, Marcelo Ramalho-Ortigão, José M. C. Ribeiro, Gustavo F. Martins   +6 more
doaj   +1 more source

Toxicity and cytotoxicity of the insecticide imidacloprid in the midgut of the predatory bug, Podisus nigrispinus.

Ecotoxicology and Environmental Safety, 2019
The selectivity of insecticides on natural enemies in pest control are an important strategy for Integrated Pest Management. However, insecticides can have side effects on non-target organisms such as natural enemies.
L. C. Martínez, A. Plata-Rueda, W. G. Gonçalves, André Filipe Penha Aires Freire, J. Zanuncio, H. Bozdoğan, J. Serrão   +6 more
semanticscholar   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

A megalin-like receptor is involved in protein endocytosis by Bombyx mori midgut cells in culture

, 2008
Protein absorption by the insect midgut currently attracts increasing research efforts, in part fostered by the need to develop efficient strategies for oral delivery of bioinsecticides targeting haemocoelic receptors.
S. Rodighiero, G. Cermenati, F. Pennacchio, M. Casartelli, B. Giordana   +4 more
core   +2 more sources

In situ analysis of pH gradients in mosquito larvae using non-invasive, self-referencing, pH-sensitive microelectrodes

, 2001
The alkaline environment, pH approximately 11, in the anterior midgut lumen of mosquito larvae is essential for normal nutrition and development. The mechanism of alkalization is, however, unknown.
Moroz, L.L., Smith, P.J., Linser, P.J., Boudko, D.Y., Trimarchi, J.R., Harvey, W.R.   +5 more
core   +1 more source

An alternative mode of epithelial polarity in the Drosophila midgut

bioRxiv, 2018
Apical-basal polarity is essential for the formation and function of epithelial tissues, whereas loss of polarity is a hallmark of tumours. Studies in Drosophila have identified conserved polarity factors that define the apical (Crumbs, Stardust, Par-6 ...
Jia Chen, A. Sayadian, N. Lowe, Holly E. Lovegrove, D. St Johnston   +4 more
semanticscholar   +1 more source

Soil‐derived, gut‐dominant generalist bacteria shape the fitness of folivorous larvae

iMeta, EarlyView.
Whether Lepidoptera harbor a conserved core gut microbiome has long remained contentious. Through large‐scale microbiome profiling of folivorous larvae, their host plants, and associated soils across three climatically distinct regions of China, we identify two soil‐derived generalist bacteria, Ralstonia insidiosa and Delftia sp., that colonize 97.92 ...
Yu‐xuan Zheng, Ying Wang, Xiao‐man Zhang, Qian Jin, Yan Zhang, Gui‐fang Wang, Yong‐qi Shao, Jing Li, Cheng Sun, Wei‐dong Kong, Cai‐qing Yang, Ai‐bing Zhang   +11 more
wiley   +1 more source

De novo apical domain formation inside the Drosophila adult midgut epithelium

eLife, 2022
In the adult Drosophila midgut, basal intestinal stem cells give rise to enteroblasts that integrate into the epithelium as they differentiate into enterocytes.
Jia Chen, Daniel St Johnston
doaj   +1 more source