Results 81 to 90 of about 77,813 (254)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Lipase and invertase activities in midgut and salivary glands of Chilo suppressalis (Walker) (Lepidoptera, Pyralidae), rice striped stem borer [PDF]

Invertebrate Survival Journal, 2008
The rice striped stem borer, Chilo supprressalis, was introduced to Iran in 1973 where it is now widely distributed and causes severe damages. Lipases, which catalyses the hydrolysis of fatty acid ester bonds, are widely distributed among animals, plants
A Zibaee, AR Bandani, S Ramzi
doaj  

Advances in research on autophagy in the maintenance of insect–microbe symbiosis

New Plant Protection, EarlyView.
Autophagy plays a dual regulatory role in insect–microbe symbiotic relationships. Beneficial symbiotic bacteria in insects participate in nutrient exchange via the TOR pathway, whereas pathogenic microbes induce immune defense through the AMPK pathway. Autophagy‐related genes regulate development and pathogen clearance during this process.
Yanbin Wang, Yuqiong Hao, Ke Chen, Hongbin Zhang, Xiansheng Xie, Feirong Ren   +5 more
wiley   +1 more source

Expression of procyclin mRNAs during cyclical transmission of Trypanosoma brucei [PDF]

, 2005
<i>Trypanosoma brucei</i>, the parasite causing human sleeping sickness, relies on the tsetse fly for its transmission. In the insect, EP and GPEET procyclins are the major surface glycoproteins of procyclic (midgut) forms of the parasite ...
J. David Barry, Blundell, Pat, Erik Vassella, Isabel Roditi, Blundell, P., Simon Urwyler, Abbeele Jan Van Den, Urwyler, Simon, Pat Blundell, Roditi Isabel, Vassella, Erik, Barry, J. David, Barry, J. D., Kunz Renggli, Christina, Abbeele, Jan Van Den, Barry, J.D., Roditi, Isabel, Jan Van Den Abbeele, Urwyler Simon, J David Barry, Van den Abbeele, J., Roditi, I., Abbeele, J.V.D., Kunz Renggli, C., Renggli Christina Kunz, Christina Kunz Renggli, Barry J. David, Vassella, E., Urwyler, S., Vassella Erik, Blundell Pat   +30 more
core   +3 more sources

Comprehensive Identification and Characterization of Long Non-coding RNAs Associated With Rice Black-Streaked Dwarf Virus Infection in Laodelphax striatellus (Fallén) Midgut

Frontiers in Physiology, 2020
Long non-coding RNAs (lncRNAs) are involved in a variety of biological functions through transcriptional and post-transcriptional regulation. However, little is known about their functions in the process of insect mediated virus transmission.
Jian-Hua Zhang, Yan Dong, Yan Dong, Wei Wu, Dian-Shan Yi, Man Wang, Hai-Tao Wang, Hai-Tao Wang, Qiu-Fang Xu, Qiu-Fang Xu   +9 more
doaj   +1 more source

Regulation of midgut cell proliferation impacts Aedes aegypti susceptibility to dengue virus

bioRxiv, 2018
Aedes aegypti is the vector of some of the most important vector-borne diseases like Dengue, Chikungunya, Zika and Yellow fever, affecting millions of people worldwide.
M. Taracena, Vanessa Bottino-Rojas, Octávio A. C. Talyuli, A. B. Walter-Nuno, J. H. Oliveira, Yesseinia I. Anglero-Rodriguez, M. Wells, G. Dimopoulos, P. Oliveira, G. Paiva-Silva   +9 more
semanticscholar   +1 more source

Targeting UDP‐Bta06664 in Bemisia tabaci: A novel strategy to reduce tomato yellow leaf curl virus transmission by impairing insect vector feeding

New Plant Protection, EarlyView.
Tomato yellow leaf curl virus upregulates the Bemisia tabaci UDP‐glycosyltransferase gene UDP‐Bta06664. RNA interference (RNAi) silencing of this gene disrupts phloem feeding—delaying E1 and shortening E2—and reduces both virus acquisition and inoculation, highlighting its potential as an RNAi target.
Zeyu Wan, Liping Huang, Zhanhong Zhang, Xuguo Zhou, Yong Liu, Xiaobin Shi   +5 more
wiley   +1 more source

Cell penetration and electrophysiological effects of an insect parvovirus in the midgut of Spodoptera frugiperda

, 2008
Densoviruses (DNV) are insect parvoviruses sharing with that group a non enveloped 20-25 nm icosaedric capsid and a single stranded DNA genome. Since they are lethal for several insects at larval stages, including agronomical pests and insects vector ...
G. Cermenati, M. Ogliastro, M. Casartelli, B. Giordana, L. Fiandra   +4 more
core   +2 more sources

Proteolytic activity in the midgut of Ectomyelois ceratoniae Zeller (Lepidoptera: Pyralidae), Pomegranate carob moth [PDF]

Invertebrate Survival Journal, 2011
In this study, the proteolytic activity in the midgut of Ectomyelois ceratoniae as the major pest of pomegranate was investigated to find nature of specific proteases and their properties for adopting possible pest management procedure. It was found that
M Ranjbar, JJ Sendi, A Zibaee
doaj  

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

Pest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus, Liina Soonvald, Iris Callewaert, Ana Isabel Silva, Ericmar Ávila Dos Santos, Silva Vilumets, Riina Kaasik, Sven Vereecken, Lenny Van Daele, Peter Dubruel, Jonathan Willow, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +13 more
wiley   +1 more source