Results 91 to 100 of about 5,486 (237)

Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1802-1820, June 2025.
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan   +9 more
wiley   +1 more source

Value of renal resistive index in hepatitis C virus related liver cirrhosis and its response to midodrine

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2014
Background: Hyperdynamic circulatory state in liver cirrhosis is characterized by increased splanchnic blood flow and renal vasoconstriction. Aim: To evaluate the relationship between renal resistive indices (RI) and HCV liver cirrhosis severity and RI ...
Sameh Ahmed Abdel-bary   +4 more
doaj   +1 more source

Male sexual dysfunction and infertility associated with neurological disorders [PDF]

open access: yes, 2011
Normal sexual and reproductive functions depend largely on neurological mechanisms. Neurological defects in men can cause infertility through erectile dysfunction, ejaculatory dysfunction and semen abnormalities.
Beckett, Nancy L.   +5 more
core   +1 more source

Recurrent Intradialytic Hypotension, Associated Risk Factors, and Outcomes in Northern Tanzania: A Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Intradialytic hypotension (IDH) is a common phenomenon during hemodialysis (HD), with profound complications and all‐cause mortality. Data on IHD is scarce in Sub‐Saharan Africa. The study aimed to evaluate the incidence, risk factors, and outcome associated with recurrent IDH among patients on maintenance HD.
Fuad H. Said   +14 more
wiley   +1 more source

Updates on potential therapeutic targets in MSA

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2016
Research into the genetic and molecular mechanisms underlying MSA has grown significantly in recent years. No neurorestorative treatments for MSA are available to date but there are many ongoing trials targeting α-syn pathways.
Viorica Chelban   +2 more
doaj   +1 more source

Droxidopa as an effective treatment for refractory neurogenic orthostatic hypotension and reflex bradycardia in amyloid light-chain amyloidosis: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Droxidopa is an oral treatment for the stepwise treatment of neurogenic orthostatic hypotension from autonomic dysfunction. It has been shown to be useful predominantly with neurogenic orthostatic hypotension secondary to Parkinson’s disease ...
Annie H. Ho   +4 more
doaj   +1 more source

Exaggerated blood pressure response to dynamic exercise despite chronic refractory hypotension : results of a human case study [PDF]

open access: yes, 2015
BACKGROUND: Chronic refractory hypotension is a rare but significant mortality risk in renal failure patients. Such aberrant physiology usually deems patient unfit for renal transplant surgery.
Higgins, Rob   +6 more
core   +1 more source

Midodrine Hydrochloride in Patients on Hemodialysis with Chronic Hypotension

open access: yesRenal Failure, 1996
Chronic hypotension, volume nonresponsive, is not rare in hemodialysis patients and is usually refractory to various therapies. Midodrine hydrochloride is an alpha-mimetic drug acting directly on the peripheral alpha-receptor and increases blood pressure.
Chiu-Ching Huang, Ji-Tseng Fang
openaire   +3 more sources

Intradialytic hypotension: Frequency, sources of variation and correlation with clinical outcome [PDF]

open access: yes, 2014
Intradialytic hypotension ( IH ) is a frequent complication of hemodialysis ( HD ) and is associated with increased patient mortality and cardiovascular events.
Alappan   +22 more
core   +1 more source

Hemodynamic Effects of Midodrine After Space Flight in Astronauts Without Orthostatic Hypotension [PDF]

open access: yes
Orthostatic hypotension and presyncope are common and potentially serious risks for astronauts returning from space. Susceptible subjects fail to generate an adequate adrenergic response to upright posture. The -1 adrenergic agonist, midodrine, may be an
Meck, Janice V.   +3 more
core   +1 more source

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