Results 71 to 80 of about 3,441 (189)

LIBERATE: a study protocol for midodrine for the early liberation from vasopressor support in the intensive care unit (LIBERATE): protocol for a randomized controlled trial

open access: yesTrials, 2022
Background Intravenous (IV) vasopressors to support hemodynamics are a primary indication for intensive care unit (ICU) admission. Utilization of oral vasopressor therapy may offer an alternative to IV vasopressor therapy in the ICU, thus decreasing the ...
Dawn Opgenorth   +12 more
doaj   +1 more source

Low‐Dose vs. Standard Care Iv Human Albumin During Large‐Volume Paracentesis in Patients With Liver Cirrhosis: A Systematic Review

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Cirrhosis is a global health concern, with ascites being the most prevalent decompensating event. Intravenous (IV) human albumin (HA) is administered during large‐volume paracentesis (LVP) to prevent complications. The standard (6–8 g HA/L ascites) is empirically chosen, potentially leading to overtreatment and added costs.
Kimberly K. I. M. Bot   +3 more
wiley   +1 more source

Midodrine to optimize heart failure therapy in patients with concurrent hypotension

open access: yesSAGE Open Medical Case Reports, 2022
According to the Centers for Disease Control and Prevention statistics, about 6.2 million adults in the United States have heart failure. Guideline-Directed Medical Therapy (GDMT) involving the use of renin-angiotensin-aldosterone system inhibitors with ...
Paul Shiu   +2 more
doaj   +1 more source

Decreased Myocardial 123I‐MIBG Uptake Without Sympathetic Denervation: An Autopsy Report of Autoimmune Autonomic Ganglionopathy

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Autopsy findings in autoimmune autonomic ganglionopathy (AAG) revealed preserved thoracic sympathetic ganglia, intact cardiac sympathetic fibers, and preserved enteric plexuses, providing pathological support for AAG as a channelopathy. Abstract Introduction Autoimmune autonomic ganglionopathy (AAG) is a rare disorder characterized by widespread ...
Daisuke Taniguchi   +7 more
wiley   +1 more source

Oncosexology: A Narrative Review on Sexual Health and Quality of Life in Cancer Patients

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer remains a major global public health problem. A key aspect of cancer care among survivors is sexual health. Cancer patients experience a range of sexual dysfunctions, including erectile dysfunction, vaginal dryness, dyspareunia, and reduced libido.
Pasquale Marino   +8 more
wiley   +1 more source

Hemodynamic Effects of Midodrine After Space Flight in Astronauts Without Orthostatic Hypotension [PDF]

open access: yes, 2006
Orthostatic hypotension and presyncope are common and potentially serious risks for astronauts returning from space. Susceptible subjects fail to generate an adequate adrenergic response to upright posture. The -1 adrenergic agonist, midodrine, may be an
Waters, Wendy W.   +3 more
core   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Postprandial Hypotension—Methods for the Evaluation and Management

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 4, April 2026.
Postprandial hypotension (PPH) is highly prevalent in older patients; however, its diagnosis remains challenging due to the absence of a consensus guideline for diagnostic criteria. Lifestyle modification is the first‐line management, taking into account the pathophysiology underlying PPH and the coexisting conditions of orthostatic hypotension and ...
Joji Ishikawa   +3 more
wiley   +1 more source

Review of adjunctive midodrine to facilitate weaning intravenous vasopressors in critically ill patients [PDF]

open access: yes, 2020
Background/Purpose: Intravenous (IV) vasopressor agents are mainstay therapy for the management of refractory hypotension in critically ill patients in the intensive care unit (ICU).
Gopalani, Radhan   +4 more
core   +1 more source

Determination of Midodrine and its Active Metabolite Desglymidodrine by LC-MS/MS and its Application in Human Pharmacokinetic Studies [PDF]

open access: yes, 2019
Background: Midodrine (MD) is a prodrug which is converted into Desglymidodrine (DMD) after oral administration. </P><P> Objective: The aim of the present study is to develop and validate a precise, accurate liquid chromatography- tandem ...
Karthik Yamjala   +4 more
core   +1 more source

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