Results 91 to 100 of about 3,700 (182)

Determination of Midodrine and its Active Metabolite Desglymidodrine by LC-MS/MS and its Application in Human Pharmacokinetic Studies

, 2019
Background: Midodrine (MD) is a prodrug which is converted into Desglymidodrine (DMD) after oral administration. </P><P> Objective: The aim of the present study is to develop and validate a precise, accurate liquid chromatography- tandem ...
Karthik Yamjala, S.J. Ashwini, B. Babu, S.T. Narenderan, S.N. Meyyanathan   +4 more
core   +1 more source

Failure of pacemaker therapy in a pediatric patient with neurally mediated complete heart block and syncope: A case report

Clinical Case Reports
Key Clinical Message Neurally mediated syncope (NMS) is a well‐known condition that can be subdivided into three subgroups: vasopressor type, cardioinhibitory type, and mixed type. While different degrees of sinus bradycardia occur at the time of syncope
Mohammad Dalili, Feisal Rahimpoor
doaj   +1 more source

Midodrine prevents orthostatic intolerance associated with simulated spaceflight

, 2001
Many astronauts after being weightless in space become hypotensive and presyncopal when they assume an upright position. This phenomenon, known as orthostatic intolerance, may interfere with astronaut function during reentry and after spaceflight and ...
Richard J. Cohen, Derin Sherman, Daniel Bloomfield, Siri Rostoft, Karin Toska, Gordon H. Williams, Craig D. Ramsdell, Thomas J. Mullen, Grete H. Sundby, Nikolai Aljuri, Janice Yelle, Natalie Sheynberg, Ming Maa, Ramakrishna Mukkamala   +13 more
core   +1 more source

Late Breaking Abstracts

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

Oral Midodrine Hydrochloride for Prevention of Orthostatic Hypotension during Early Mobilization after Hip Arthroplasty:A Randomized, Double-blind, Placebo-controlled Trial

, 2015
Background: Early postoperative mobilization is essential for rapid recovery but may be impaired by orthostatic intolerance (OI) and orthostatic hypotension (OH), which are highly prevalent after major surgery.
Mehlsen, J., Josiassen, Jakob, Husted, Henrik, Josiassen, J., Kehlet, H., Mehlsen, Jesper, Kjærsgaard-Andersen, Per, Solgaard, S., Kehlet, Henrik, Lunn, T. H., Husted, H., Solgaard, Søren, Kjaersgaard-Andersen, P., Jans, Øivind, Jans, Ø., Lunn, Troels Haxholdt   +15 more
core   +1 more source

Haemodynamic effects of fludrocortisone and midodrine in patients with symptoms due to hypotension

Aim: The study aimed to assess the haemodynamic effects of fludrocortisone and midodrine, alone or combined, in patients with recurrent syncope and/or symptoms due to hypotension and ≥ 1 daytime systolic blood pressure (SBP) drop < 90 mmHg or ≥ 2 ...
van Zanten S., Parati G., Fedorowski A., Nawaz S., Groppelli A., Ungar A., Russo V., Maggi R., Comune A., Brignole M., de Lange F. J., Rivasi G., Capacci M.   +12 more
core   +1 more source

Noradrenalin Versus the Combination of Midodrine and Octreotide in Patients with Hepatorenal Syndrome: Randomized Clinical Trial

International Journal of Preventive Medicine, 2012
Background: Hepatorenal syndrome (HRS) is known as development of acute renal failure in a patient who usually has advanced liver disease. The aim of the present study was to determine the safety and the efficacy of noradrenalin in comparison with ...
Hamid Tavakkoli, Kambiz Yazdanpanah, Marjan Mansourian   +2 more
doaj  

Midodrine‐Associated Posterior Reversible Encephalopathy Syndrome Following Medullary and Cervical Spinal Cord Infarction in a Child

Introduction Posterior reversible encephalopathy syndrome (PRES) is a clinico‐radiological syndrome driven by disrupted cerebral autoregulation, typically in the setting of acute hypertension, toxic drug exposure, or endothelial ...
Shivam Rainchwar, Ankit Khetan, Ratish Juyal, Kamalesh Tayade, Shardool Gadgil   +4 more
core   +1 more source

Outcomes with inpatient use of midodrine in patients with heart failure and kidney failure on maintenance dialysis

BACKGROUND: Midodrine, an FDA-approved medication for orthostatic hypotension, is also used off-label to manage hypotension in dialysis patients, including those with heart failure. However, in patients with reduced ejection fraction (HFrEF) and/or right
Alvarez Concejo, Bruno, Patel, Neev, Lo, Kevin Bryan, Rangaswami, Janani, Kattubadi, Ayeesha, Mishra, Meenakshi   +5 more
core   +1 more source

Midodrine versus placebo in patients with acute-on-chronic liver failure with ascites-A randomized trial (MIDAS trial). [PDF]

Hepatol Commun
Kulkarni AV, Venishetty S, Prasanna S, Iyengar S, Sarada SV, Premkumar M, Sharma M, Alla M, Rao PN, Reddy DN, Reddy KR.   +10 more
europepmc   +1 more source