Results 71 to 80 of about 6,145 (277)

Treatment of Cirrhosis-Associated Hyponatremia with Midodrine and Octreotide [PDF]

Frontiers in Medicine, 2017
Hyponatremia in the setting of cirrhosis is a common electrolyte disorder with few therapeutic options. The free water retention is due to non-osmotic vasopressin secretion resulting from the cirrhosis-associated splanchnic vasodilatation. Therefore, vasoconstrictive therapy may correct this electrolyte abnormality.
Minh-Kevin Nguyen, Minhtri K. Nguyen, Sharad Patel, Dai-Scott Nguyen, Anjay Rastogi   +4 more
openaire   +3 more sources

Midodrine as a Countermeasure for Post-Spaceflight Orthostatic Hypotension [PDF]

, 2008
One possible mechanism for post-spaceflight orthostatic hypotension, which affects approximately 30% of astronauts after short duration shuttle missions, is inadequate norepinephrine release during upright posture.
Meck, Janice V., Platts, Steven H., Stein, Sydney P., Stenger, Michael B.   +3 more
core   +1 more source

Systematic review with meta-analysis: vasoactive drugs for the treatment of hepatorenal syndrome type 1 [PDF]

, 2017
Background Hepatorenal syndrome type 1 (HRS1) is a functional, rapidly progressive, potentially reversible form of acute kidney injury occurring in patients with cirrhosis.
Alessandria, Angeli, Arroyo, Belcher, Belcher, Besso, Boyer, Cavallin, Fernández, Gillies, Gluud, Hadengue, Mandal, Marik, Martin-Llahi, Martin-Llahi, Mattos, Moher, Navasa, Neri, Newby, Platt, Ruiz-del-Arbol, Salerno, Salerno, Salmeron, Sanyal, Schepke, Sharma, Silawat, Singh, Solanki, Srivastava, Tavakkoli, Wood   +34 more
core   +2 more sources

Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan, Ciara Kirke, Leon O'Hagan, Frank Moriarty, Kevin D. Murphy, Laura J. Sahm, Cian O'Mahony, Emma J. Coyle, Stephen Byrne, Kieran Dalton   +9 more
wiley   +1 more source

Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals [PDF]

, 2010
Classical antiviral therapies target viral proteins and are consequently subject to resistance. To counteract this limitation, alternative strategies have been developed that target cellular factors.
Bruno Lina, Béatrice Loriod, Catherine N'Guyen, Jean-Jacques Diaz, Julien Textoris, Laurence Josset, Man-Seong Park, Manuel Rosa-Calatrava, Olivier Ferraris, Vincent Moules   +9 more
core   +8 more sources

Syncope: Advances in Diagnosis and Treatment 2024

Journal of Cardiovascular Electrophysiology, EarlyView.
Vasovagal syncope advances in therapy. ABSTRACT Aim In light of many recent advances in the field of vasovagal syncope, a selective review has been undertaken of these developments. Methods Recent publications on the following topics were reviewed; understanding of vasovagal syncope pathophysiology, tilt‐testing methodology and interpretation, drug ...
Richard Sutton, Rose Anne Kenny, David G. Benditt   +2 more
wiley   +1 more source

The Impact of Midodrine on Guideline-Directed Medical Therapy in Patients Admitted With Systolic Heart Failure

medRxiv, 2023
: Midodrine is occasionally used off-label to treat hypotension associated with advanced heart failure (HF); however, its association with changes in prescription of guideline-directed medical therapy (GDMT) is unknown.
Christopher B Scoma, Dae Hyun Lee, David B Money, G. Eichelberger, A. Usmani, Adam J Cohen, Joel Fernandez   +6 more
semanticscholar   +1 more source

LIBERATE: a study protocol for midodrine for the early liberation from vasopressor support in the intensive care unit (LIBERATE): protocol for a randomized controlled trial

Trials, 2022
Background Intravenous (IV) vasopressors to support hemodynamics are a primary indication for intensive care unit (ICU) admission. Utilization of oral vasopressor therapy may offer an alternative to IV vasopressor therapy in the ICU, thus decreasing the ...
Dawn Opgenorth, Nadia Baig, Kirsten Fiest, Constantine Karvellas, Jim Kutsogiannis, Vincent Lau, Erika Macintyre, Janek Senaratne, Jocelyn Slemko, Wendy Sligl, Xiaoming Wang, Sean M. Bagshaw, Oleksa G. Rewa   +12 more
doaj   +1 more source

Should midodrine be used as an intravenous vasopressor-sparing agent in septic shock?

Cleveland Clinic journal of medicine, 2023
Research and robust data are still lacking regarding use of midodrine in this setting.
Simran Gupta, Ayan Sen, Aman Verma
semanticscholar   +1 more source

Midodrine to optimize heart failure therapy in patients with concurrent hypotension

SAGE Open Medical Case Reports, 2022
According to the Centers for Disease Control and Prevention statistics, about 6.2 million adults in the United States have heart failure. Guideline-Directed Medical Therapy (GDMT) involving the use of renin-angiotensin-aldosterone system inhibitors with ...
Paul Shiu, Gurinder S Grewal, Teri M Kozik   +2 more
doaj   +1 more source