Results 81 to 90 of about 4,834 (179)
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Annals of Neurology, Volume 98, Issue 5, Page 991-1003, November 2025.Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam +29 more
wiley +1 more source
Al-Azhar Assiut Medical Journal, 2016 Background Portal hypertension, which occurs as a consequence of liver cirrhosis, leads to splenic vasodilatation and alterations in the systemic circulation.
Hamdy M Moustafa +3 more
doaj +1 more source
Intradialytic hypotension: Frequency, sources of variation and correlation with clinical outcome [PDF]
, 2014 Intradialytic hypotension ( IH ) is a frequent complication of hemodialysis ( HD ) and is associated with increased patient mortality and cardiovascular events.
Alappan +22 more
core +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2014 Background: Hyperdynamic circulatory state in liver cirrhosis is characterized by increased splanchnic blood flow and renal vasoconstriction. Aim: To evaluate the relationship between renal resistive indices (RI) and HCV liver cirrhosis severity and RI ...
Sameh Ahmed Abdel-bary +4 more
doaj +1 more source
Updates on potential therapeutic targets in MSA
Advances in Clinical Neuroscience & Rehabilitation, 2016 Research into the genetic and molecular mechanisms underlying MSA has grown significantly in recent years. No neurorestorative treatments for MSA are available to date but there are many ongoing trials targeting α-syn pathways.
Viorica Chelban +2 more
doaj +1 more source
Risk of Orthostatic Intolerance During Re-Exposure to Gravity [PDF]
Post-spaceflight orthostatic intolerance remains a significant concern to NASA. In Space Shuttle missions, astronauts wore anti-gravity suits and liquid cooling garments to protect against orthostatic intolerance during re-entry and landing, but in ...
Arzeno, Natalia M. +7 more
core +1 more source
Midodrine as a Countermeasure to Orthostatic Hypotension Immediately After Space Shuttle Landing [PDF]
Midodrine prevents post-space flight orthostatic intolerance when testing is conducted in a controlled laboratory setting within 2-4 hours after Space Shuttle landing.
Lee, Stuart M. C. +3 more
core +1 more source
Evidence-based de-implementation for contradicted, unproven, and aspiring healthcare practices [PDF]
, 2014 Abandoning ineffective medical practices and mitigating the risks of untested practices are important for improving patient health and containing healthcare costs.
John PA Ioannidis, Vinay Prasad
core +1 more source
Journal of Research in Medical Sciences, 2011 Background: In cirrhotic patients peripheral vasodilatation may decrease renal blood flow and subsequently raises plasma renin activity. Octreotide with several mechanisms causes peripheral arterial vasoconstriction.
Mohammad Minakari +3 more
doaj
Cough syncope treated with midodrine hydrochloride: one case report
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 DOI：10.3969/j.issn.1672⁃6731.2020.05 ...
Tao LIANG +5 more
doaj