MIF Deficiency Modulates Gut Microbiota Composition and Promotes Colitis-Associated Colorectal Cancer in a Murine Model. [PDF]
H Navia S +9 more
europepmc +1 more source
A Functionally Constrained Immune Ecosystem in Microsatellite-stable Colorectal Cancer Resolved by Single-cell and Exome Profiling. [PDF]
Liu W +6 more
europepmc +1 more source
Macrophage migration inhibitory factor in atrial fibrillation. [PDF]
Wu X +8 more
europepmc +1 more source
Allele‐Specific GNAQ Q209 Mutations Reveal Context‐Dependent Oncogenic Programs in Uveal Melanoma
Using matched immune‐competent, multistep uveal melanoma models, we show that GNAQ Q209L and Q209R mutations are not functionally equivalent. Q209L drives faster in vivo progression but reduces in vitro proliferation and migration, whereas Q209R promotes greater in vitro fitness and preferential FAK‐YAP activation, revealing an allele‐dependent ...
Vinesh Jarajapu +5 more
wiley +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
STING expression in pituitary neuroendocrine tumour immune microenvironments. [PDF]
Loughrey PB +13 more
europepmc +1 more source
Barrier‐Assisted Plasma Doping for Spatially Selective Resistance Engineering in MoS2 Transistors
Barrier‐assisted NH3 plasma doping enables damage‐free, spatially selective carrier modulation in monolayer MoS2 transistors. An ultrathin pV3D3/Al2O3 protective‐dielectric stack acts as a chemical filter that allows NHx radicals to reach the MoS2 surface while blocking plasma damage. This process achieves a high electron concentration of 4.3 × 1013 cm−
Inseong Lee +15 more
wiley +1 more source
Integrated Single-Cell and Spatial Transcriptomic Analysis Reveals the Immunoregulatory Role of MIF Signaling in Colorectal Cancer. [PDF]
Liu Y +5 more
europepmc +1 more source
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source
MIF-Associated Immunosuppressive CAF Remodeling Predicts Poor Prognosis During Lung Adenocarcinoma Progression: A Single-Cell and Multicohort Transcriptomic Study. [PDF]
Lin G, Ji J, Ge F, Hui Z.
europepmc +1 more source

