Results 191 to 200 of about 44,246 (295)

Integrated Multi‐Omics and Single‐Cell Analyses Implicate NOX4 as an Icariin‐Associated Oxidative Stress Regulatory Node in Gastric Cancer

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
NOX4 represents a candidate icariin‐associated regulatory node in gastric cancer and may contribute to the cellular response to icariin through redox‐related signaling. ABSTRACT Icariin, a prenylated flavonoid glycoside from Epimedium species, is a representative dietary polyphenol with antioxidant, anti‐inflammatory, and antitumor properties.
Na Liang, Junyan Li, Zuchao Luo, Zijuan Song, Liyuan Zhang, Chengyi Zou, Chunming Li, Bochen Pan, Jiawei Yang   +8 more
wiley   +1 more source

Multiomic analysis identifies T cell subsets and mechanisms of epithelial interaction in idiopathic pulmonary fibrosis. [PDF]

JCI Insight
Serezani AP, Bazzano JM, Pascoalino BD, da Silva L, Dietrich AJ, Taylor CJ, Sherrill T, Vannan A, Calvi CL, Gonzalez-Ericsson PI, Wilfong EM, Bacchetta M, Shaver CM, Ware LB, Salisbury ML, Van Kaer L, Banovich NE, Kropski JA, Blackwell TS.   +18 more
europepmc   +1 more source

Trends in Aeroallergen IgE Sensitization in Jordan: A Decade‐Long Observational Study

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Background Inhalant allergies from airborne allergens, such as pollen, dust mites, and animal dander, substantially contribute to allergic respiratory diseases globally. Sensitization to aeroallergens is influenced by environmental, urban, and climatic factors and demographic characteristics, including age and sex. However, long‐term data from
Jumana Abu‐Kwaik, Aymen Rawashdeh, Badia Saddedin, Mohammad Ghunaim, Thaer Hasan, Amid Abdelnour, Issa Abu‐Dayyeh   +6 more
wiley   +1 more source

Helminth proteins recapitulate key structural motifs of MIF to facilitate immunomodulation of host receptors. [PDF]

iScience
Orkwis JA, Manjula R, Lolis EJ.
europepmc   +1 more source

Enrichment and Proteomic Profiling of Stromal‐Associated Extracellular Vesicle Subpopulations From Arthritic Synovial Fluid by Size‐Exclusion Chromatography Coupled to CD90‐Directed Immunocapture

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Synovial fluid contains heterogeneous EV populations reflecting stromal and immune‐associated cellular inputs from the arthritic joint. SEC‐UF enrichment coupled to CD90‐targeted immunocapture enables recovery of stromal‐associated EV subpopulation from complex patient synovial fluid, while focused LC‐MS/MS and cell‐of‐origin analysis enable molecular ...
Stefanie Kurth, Edveena Hanser, Simone Häner‐Massimi, Stavros Giaglis, Florian Geier, Dominik Burri, Katarzyna Buczak, Ute Heider, Stefan Wild, Yves P. Acklin, Christian Egloff, André N. Tiaden, Diego Kyburz   +12 more
wiley   +1 more source

Disruption of macrophage migration inhibitory factor signaling induces major tumor-associated macrophage phenotypes in human M2 macrophages. [PDF]

Mol Biomed
Klaver D, Gander H, Frena B, Martin M, Amato M, Richter J, Pichler R, Thurnher M.   +7 more
europepmc   +1 more source

C1qc Mediates Blood–Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia‐Derived Migrasomes

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Microglia‐derived migrasomes induce vascular endothelial pyroptosis through C1qc delivery, uncovering a novel mechanism of blood–brain barrier (BBB) disruption after intracerebral haemorrhage (ICH) and proposing a novel therapeutic strategy targeting extracellular vesicles (EVs).
Mengyuan Li, Zhihua Li, Dengpan Song, Fang Wang, Mengzhao Feng, Chi‐Tai Yeh, Tingting Zhai, Menghan Deng, Yanyan Sun, Junyang Wang, Xuemei Chen, Yating Wang, Qiong Yang, Moxin Wu, Xiaoping Yin, Junmin Wang, Jian Wang, Fuyou Guo   +17 more
wiley   +1 more source

Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
The immunosuppressive in OM Staphylococcus aureus employs multiple physical barriers to evade host immunity during skeletal infection, including biofilm formation on implant surfaces and necrotic bone tissues, invasion into the osteocyte lacuno‐canalicular network (OLCN), intracellular persistence within osteoblasts, osteoclasts, and osteocytes, and ...
Qingqiang Lei, Liangbin Lin, Peidong Pu, Jie Chen, Xianchao Su, Shubao Liu, Yanli Tong, Hui Yu   +7 more
wiley   +1 more source

Integrative multi-omics analysis prioritizes ALDH2 as a candidate Puerarin-associated target linked to macrophage infiltration in lung adenocarcinoma. [PDF]

Front Immunol
Chen Y, Zhong Z, Ju G, Cai Y, Zhou L, Wang Q, Yang B.   +6 more
europepmc   +1 more source