Results 211 to 220 of about 44,246 (295)
Probing pyrazolo-pyrimidines as SIRT2 inhibitors <i>via</i> molecular modelling and biological assays. [PDF]
Musumeci F +12 more
europepmc +1 more source
Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du +9 more
wiley +1 more source
Using 38 blood SASP proteins, a guided autoencoder‐transformer model generates a composite SASP Score that captures systemic cellular senescence burden. The score predicts mortality and age‐related diseases, outperforms individual proteins, and supports cross‐platform biomarker translation.
Shangshu Zhao +9 more
wiley +1 more source
Associations of TNF-α, MIF, and cortisol with cognitive function in patients with bipolar disorder during acute manic episodes: a short-term follow-up study. [PDF]
Tang H, Lin S, Liu X, Chen J, Zuo X.
europepmc +1 more source
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam +4 more
wiley +1 more source
Magnetic field-assisted immersion freezing preserves starch structure and quality of fresh waxy corn puree. [PDF]
Fan J +9 more
europepmc +1 more source
MIF in innate immunity and infectious diseases.
Roger, T, Kaech, C, Calandra, T
core +1 more source
Single-Cell and Spatial Transcriptomics Identify the Mono-S100A4 Subset Associated with Sepsis-Induced Lung Injury via the MIF-(CD74+CD44) Axis. [PDF]
Wang A +10 more
europepmc +1 more source
Single‐cell and multi‐omics analyses identified THBS1+ macrophages as a terminally differentiated, hypoxia‐adaptive population driving coronary atherosclerosis through THBS1‐CD36 signaling with lymphatic endothelial cells. Targeting CD36 with SMS121 and leveraging a THBS1+ macrophage gene signature enabled therapeutic prediction and accurate risk ...
Jianpeng Li +4 more
wiley +1 more source

