Single-cell reanalysis highlights the MIF-PTGDR axis as a candidate immunoregulatory program in hepatocellular carcinoma. [PDF]
Liu D, Yan L, Chen H, Yuan L.
europepmc +1 more source
mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation
ABSTRACT Skin aging is a multifactorial process characterized by the progressive decline of tissue structure, function and regenerative capacity. Although numerous interventions have been developed to improve the clinical manifestations of aging, most primarily alleviate downstream consequences rather than directly targeting the molecular mechanisms ...
Fabiana Boncimino +3 more
wiley +1 more source
Multiomics Analysis Reveals CTHRC1+ CAFs Drive Immunosuppressive Niches and Predict Immunotherapy Resistance in Gastric Cancer. [PDF]
Wu Y +7 more
europepmc +1 more source
ABSTRACT Aging is a systemic decline in physiological integrity, driving chronic diseases such as neurodegeneration, cardiovascular disorders, and metabolic syndromes. Rapid global population aging urgently demands effective interventions. Traditional Chinese medicine (TCM) formulas, characterized by multi‐component, multi‐target, and multi‐pathway ...
Chenrong Jin +10 more
wiley +1 more source
LUCID: Intelligent Informative Frame Selection in Otoscopy for Enhanced Diagnostic Utility. [PDF]
Lu H +11 more
europepmc +1 more source
Tocilizumab for severe and refractory mucous membrane pemphigoid
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Billal Tedbirt +20 more
wiley +1 more source
Coordinated Expression of ADC Targets <i>ERBB2</i>, <i>TACSTD2</i>, and <i>NECTIN4</i> in Bladder Cancer: A Multi-Scale Transcriptomic and Proteomic Landscape Analysis. [PDF]
Liu S, Duan L, Wei S.
europepmc +1 more source
Correction: MIF/CD74 axis is a target for novel therapies in colon carcinomatosis. [PDF]
Bozzi F +16 more
europepmc +1 more source
Aerobic exercise is associated with divergent regulation of macrophage migration inhibitory factor and enhanced remyelination in experimental autoimmune neuritis. [PDF]
Liu Y +11 more
europepmc +1 more source

