Results 61 to 70 of about 44,246 (295)

Pro-inflammatory action of MIF in acute myocardial infarction via activation of peripheral blood mononuclear cells.

PLoS ONE, 2013
ObjectivesMacrophage migration inhibitory factor (MIF), a pro-inflammatory cytokine, has been implicated in the pathogenesis of multiple inflammatory disorders.
David A White, Lu Fang, William Chan, Eric F Morand, Helen Kiriazis, Stephen J Duffy, Andrew J Taylor, Anthony M Dart, Xiao-Jun Du, Xiao-Ming Gao   +9 more
doaj   +1 more source

MIF interacts with HIF1α.

, 2015
(A) Cellular localization of HIF1α (green) and MIF (red) in cells treated with LPA was determined by immunofluorescence confocal microscopy. TO-PRO was used for nuclear counterstaining (blue). n = 3.
Yi Ran No (793332), Sei-Jung Lee (793333), C. Chris Yun (173933), Ajay Kumar (192967)   +3 more
core   +1 more source

MIF Evaluation - Business Development Services [PDF]

, 2003
This document (MIF/GN-78-12) reports the results of OVE\u27s evaluation to MIF\u27s Business Development Services. From 1994 to 2002 a total of US$135 million were allocated for 100 Business Development Services (BDS) projects.
Inter-American Development Bank
core   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

MIF and AHP methods for delineation of groundwater potential zones using remote sensing and GIS techniques in Tirunelveli, Tenkasi District, India

Open Geosciences
The present study aims to identify whether the delineation of potential groundwater potential zones (GWPZs) is essential for monitoring surface and conserving underground water resources.
Jebaraj Samuel Prabaharan, Rajagopal Viji   +1 more
doaj   +1 more source

Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer

BMC Cancer, 2005
Background Macrophage migration inhibitory factor (MIF) is a cytokine associated with prostate cancer, based on histologic evidence and circulating (serum) levels. Recent studies from another laboratory failed to document these results. This study's aims
Iczkowski Kenneth A, Meyer-Siegler Katherine L, Vera Pedro L   +2 more
doaj   +1 more source

Evaluation of MIF Projects: Environment [PDF]

, 2004
This report (MIF/GN-78-13) is the outcome of evaluation of a group of 17 MIF environment projects, as part of the work program of the Office of Evaluation and Oversight (OVE) to evaluate MIF activities, following the mandate of its Donors Committee.
Inter-American Development Bank
core   +1 more source

Receptor binding and cellular uptake studies of macrophage migration inhibitory factor (MIF): Use of biologically active labeled MIF derivatives

, 2022
S.351-363Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine for which a receptor has not been identified. That MIF has intracellular functions has been suggested by its enzymatic activity and constitutive expression profile.
Kleemann, R., Bernhagen, J., Grell, M., Zimmermann, G., Mischke, R.   +4 more
core   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Macrophage Migration Inhibitory Factor Mediates PAR-Induced Bladder Pain. [PDF]

PLoS ONE, 2015
Macrophage migration inhibitory factor (MIF), a pro-inflammatory cytokine, is constitutively expressed in urothelial cells that also express protease-activated receptors (PAR). Urothelial PAR1 receptors were shown to mediate bladder inflammation.
Dimitrios E Kouzoukas, Katherine L Meyer-Siegler, Fei Ma, Karin N Westlund, David E Hunt, Pedro L Vera   +5 more
doaj   +1 more source