Results 61 to 70 of about 64,011 (298)
Contención migratoria en pandemia. Configuración territorial de detenciones y deportaciones en las fronteras de México [PDF]
REMHU: Revista Interdisciplinar da Mobilidade HumanaResumen Las poblaciones irregularizadas del Norte de Centroamérica con destino a Estados Unidos y en tránsito por México han experimentado dinámicas estatales de contención migratoria.
Guillermo Castillo Ramírez +1 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Reconsidering the migrant letter: from the experience of migrants to the language of migrants [PDF]
The History of the Family, 2016 AbstractFollowing a century of scholarly attention, the migrant letter, whether written by family members, lovers, friends, or others, is a document that continues to attract the attention of scholars and general readers. Over time, the study of migrant letters has developed in myriad directions.
Marcelo J. Borges, Sonia Cancian
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
La perspectiva estructural de la justicia y los migrantes
Bajo Palabra, 2020 Rawls definió la justicia como una virtud de la estructura básica. Las características mediante las que interpretó a esta, sin embargo, impusieron a la teoría de la justicia de graves limitaciones en cuanto a su capacidad para afrontar los nuevos ...
Francisco Blanco Brotons
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Realidad de los migrantes y refugiados en Colombia
, 2023 Como dicen por ahí… No hay como el propio país. Es cierto, para nadie es un secreto que trasladarse a otro país es una decisión que cambia la vida de una persona completamente.
Puentes Villota, Juliana, Campo Laura
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source