Results 71 to 80 of about 201,022 (311)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Considering the exploitation of migrants who sell sex: a case study of Brazilians in the Iberian sex industry [PDF]

open access: yes, 2015
Although migrants who sell sex often go through a range of situations which might be considered exploitative, such situations are not always linked with trafficking.
De Perez, JL, Vermeulen, Gert
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

A presença de mulheres negras trabalhadoras escolarizadas em periódicos mato-grossenses nos oitocentos

open access: yesRevista de Educação Pública, 2018
O artigo tem como objetivo trazer ao lume a presença de mulheres negras trabalhadoras escolarizadas em periódicos mato-grossenses no mundo do trabalho na cidade de Cuiabá-MT, final do século XIX.
Paulo Sérgio DUTRA
doaj  

Crise humanitária internacional e os direitos das crianças migrantes ou refugiadas: uma análise da Opinião Consultiva nº 21 da Corte Interamericana de Direitos Humanos

open access: yesRevista do Direito, 2017
Este artigo analisa como são assegurados os direitos humanos de crianças migrantes ou que estejam na condição de refugiadas, buscando uma aproximação do sistema internacional de proteção dos Direitos Humanos com o Direito Internacional dos Refugiados.
Fernanda Da Silva Lima
doaj   +1 more source

Feather growth rate and mass in nearctic passerines with variablemigratory behavior and molt pattern [PDF]

open access: yes, 2012
Bird species vary greatly in the duration of their annual complete feather molt. However, such variation is not well documented in birds from many biogeographic areas, which restricts our understanding of the diversification of molt strategies.
Barta Z.   +8 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Apoyo humanitario a niñas y niños repatriados: las Casas YMCA para Menores Migrantes

open access: yesRevista Latinoamericana en Ciencias Sociales, Niñez y Juventud, 2015
La repatriación de mexicanos desde Estados Unidos es una constante en el tema de las migraciones, y la asistencia a los migrantes es un aspecto relevante sobre todo cuando se trata de niñas, niños y adolescentes.
Gabriela Zamora
doaj   +1 more source

Home - About - Disclaimer - Privacy