Results 81 to 90 of about 64,011 (298)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Religiosidade e identidade na diáspora: por uma etnografia entre migrantes haitianos em Porto Velho [PDF]

open access: yes, 2016
Dissertação apresentada à Universidade Federal de Rondônia (UNIR), como requisito parcial obrigatório para a obtenção do título de Mestrado Acadêmico em Letras junto ao Departamento de Línguas Vernáculas, Núcleo de Ciências Humanas.
Ribeiro, Ailton Artur da Silva   +1 more
core  

Migrantes Ambientales: La expresión humana del Cambio Climático [PDF]

open access: yes, 2023
El cambio climático representa uno de los desafíos más apremiantes del siglo XXI y está transformando de manera significativa nuestras sociedades.
Gutiérrez Domínguez, Octavio
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Migrantes venezolanos en el Ecuador, Lejos.

open access: yes, 2017
Estudiando el tema de los migrantes venezolanos en Ecuador, obtuvimos nuestros primeros datos a través de medios de comunicación. Basado en la investigación, tuvimos un primer acercamiento con un venezolano líder de una asociación civil llamada MUEVE,
Herrera Calderon, Dustin Madison   +1 more
core  

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu   +7 more
wiley   +1 more source

Migrantes venezolanos y VIH: Perú

open access: yes, 2020
En Perú hay 1,500 migrantes venezolanos que reciben el tratamiento gratuito que otorga el Estado a los portadores del VIH. Cerca de 8,000 venezolanos portadores del VIH han abandonado su país por la crisis en búsqueda urgente de tratamientos ...
Olga Gonzalez
core  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

Symbolic Regression and Multi‐Objective Optimization of the Flory–Huggins Interaction Parameter for Hydrogels

open access: yesAdvanced Engineering Materials, EarlyView.
We develop a data‐driven method to derive the mathematical expressions of the Flory–Huggins interaction parameter χ for the swelling behavior of temperature–responsive hydrogels. Starting from initial assumptions of χ, our workflow combines Bayesian optimization, Flory–Rehner theory, and symbolic regression to generate candidate χ expressions.
Yawen Wang   +2 more
wiley   +1 more source

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