Results 111 to 120 of about 5,089,023 (378)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Commentary on session I: The migration, trade, and development nexus [PDF]

open access: yes
Summary and discussion of the three papers in this session: "The trade, migration, and development nexus" by Philip L. Martin; "External and internal determinants of development" by Thomas Osang; and "Globalization and Mexican labor markets" by Raymond ...
Kent H. Hughes
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells [PDF]

open access: bronze, 2012
Shahriar Koochekpour   +14 more
openalex   +1 more source

External and internal determinants of development [PDF]

open access: yes
As Rodrik, Subramanian, and Trebbi (2004) point out, factors that affect economic development can be classified using a two-tier approach. Based on a standard production function, inputs such as labor and physical and human capital directly affect per ...
Thomas Osang
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Mixed-citizenship couples’ emotional geographies of ‘doing family’

open access: yesComparative Migration Studies
While studies on mixed-citizenship couples predominantly focus on challenges and problems the families face because of immigration control, the emotional strategies of couples resisting exclusion remain untheorised.
Pihla Maria Siim, Eveliina Lyytinen
doaj   +1 more source

Seasonal migration of the Yellow Sea Bottom Cold Water [PDF]

open access: bronze, 2014
Bin Wang   +3 more
openalex   +1 more source

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