Results 31 to 40 of about 1,561,303 (249)
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
A Migration Project in Retrospect: The Case of the Ageing Zero Generation in Emirdağ
Social Inclusion, 2018 In the twentieth century, Emirdağ (Turkey) witnessed extensive emigration and is now home to the ‘zero generation’: a group of elderly people who stayed behind when their children moved abroad.
Christiane Timmerman +4 more
doaj +1 more source
Geoadria, 2020 This paper analyses the results of the research on housing integration as the important part of functional integration of most numerous immigrant group in Croatia – Croatian citizens who were born in Bosnia and Herzegovina. The analysed survey (CAPI) was
Sonja Podgorelec +2 more
doaj +1 more source
Inhibition of MIR4435-2HG on Invasion, Migration, and EMT of Gastric Carcinoma Cells by Mediating MiR-138-5p/Sox4 Axis [PDF]
, 2021 Li-Fei Gao +5 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Interdisciplinary Journal of Partnership Studies, 2023 Health knowledge and behaviors can impact well-being and promote community integration post-arrival for refugees and migrants being resettled. Health and hygiene curricula are efficient and accessible mechanisms to mitigate the risk of chronic and ...
Shanna Miko +8 more
doaj +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
An Overview of Anthropological Regional Studies
International Journal of Anthropology and Ethnology, 2019 Regional studies in anthropology are vital to the development of the discipline, for they supply anthropology with an approach that moves from individual cases to a holistic understanding of a region. Western anthropologists’ interests in researching non-
Daming Zhou +3 more
doaj +1 more source
Risk and Reward in Foraging Migrations of North Pacific Albacore Determined From Estimates of Energy Intake and Movement Costs [PDF]
, 2022 Barbara Muhling +7 more
openalex +1 more source