Results 81 to 90 of about 4,059,892 (292)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Flight feather moult in Western Marsh Harriers during autumn migration

Avian Research, 2019
Background Most of long-distance migratory raptors suspend moult during migration but detailed information is patchy for most of the Palearctic species.
Juan Ramírez, Michele Panuccio
doaj   +1 more source

International Migration as Absolute Natural Law: An Inquiry into International Migration from the Perspective of Legal Philosophy [PDF]

, 2016
This paper investigates to what extent international migration law is coherent with the concept of migration as a natural human right. Based on the assumption that migration is an inherently human behavior, beneficial to humankind, and therefore natural ...
Ernst, Maximilian
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

P2X7 receptor promotes migration and invasion of non-small cell lung cancer A549 cells through the PI3K/Akt pathways [PDF]

, 2023
Xue Bai, Qianqian Li, Xiaoxiang Peng, Xinyu Li, Cuicui Qiao, Yiqing Tang, Ronglan Zhao   +6 more
openalex   +1 more source

Commentary on session I: The migration, trade, and development nexus [PDF]

Summary and discussion of the three papers in this session: "The trade, migration, and development nexus" by Philip L. Martin; "External and internal determinants of development" by Thomas Osang; and "Globalization and Mexican labor markets" by Raymond ...
Kent H. Hughes
core  

Internal Migration and Regional Population Dynamics in Europe: Norway Case Study [PDF]

, 1998
This paper reports on internal migration and regional population dynamics in Norway. It examines internal migration patterns and trends in two years, 1984 and 1994, and compares them.
Durham, H., Kupiszewski, M., Orsby, L., Rees, P.   +3 more
core   +1 more source

Migration energy aware reconfigurations of virtual network function instances in NFV architectures [PDF]

, 2017
Network function virtualization (NFV) is a new network architecture framework that implements network functions in software running on a pool of shared commodity servers.
Ammar, Mostafa, Eramo, Vincenzo, Lavacca, FRANCESCO GIACINTO   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Systematic review of empiric studies on lockdowns, workplace closures, and other non-pharmaceutical interventions in non-healthcare workplaces during the initial year of the COVID-19 pandemic: benefits and selected unintended consequences

BMC Public Health
Background We conducted a systematic review aimed to evaluate the effects of non-pharmaceutical interventions within non-healthcare workplaces and community-level workplace closures and lockdowns on COVID-19 morbidity and mortality, selected mental ...
Faruque Ahmed, Livvy Shafer, Pallavi Malla, Roderick Hopkins, Sarah Moreland, Nicole Zviedrite, Amra Uzicanin   +6 more
doaj   +1 more source