Results 61 to 70 of about 10,626 (260)

Cooperation as an Essential Component of European Integrated Border Management (EIBM) [PDF]

Romanian Journal of European Affairs, 2022
The European Union has given new impetus to the European Pact on Migration and Asylum, making important progress in trying to adapt the European response to the current migratory reality.
Mustafa Ameyahid Mohamed, César Augusto Giner Alegria   +1 more
doaj  

Crossing the endothelium [PDF]

Cell Adhesion & Migration, 2008
Diapedesis is a vital part of tumor metastasis, whereby tumor cells attach to and cross the endothelium to enter the circulation. Specific adhesion molecules, expressed by both the tumor and endothelial cells, mediate this process. This review summarizes recent findings regarding the mechanisms by which colon cancer cells migrate through the ...
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Moving Borders. European Immigration Policy and the Multidimensional Instability of the Boundaries [PDF]

Romanian Journal of European Affairs, 2011
Two contemporary phenomena in the field of immigration force us to reflect upon the relationship between the migration flows and their political management: the tortuous development of the European immigration policies, and the contemporary struggles ...
Paolo Cossarini
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

DECENTRALIZATION OF INTER-BUDGET RELATIONS: THEORY, PRACTICE, AND INTERNATIONAL EXPERIENCE

Baltic Journal of Economic Studies, 2019
The purpose of the article is to justify the methods of budget policy for the redistribution of cash flows in terms of differentiating powers at different levels of government and to analyse intergovernmental regulation improvement.
Liudmyla Pidchosa, Igor Lyutyy, Oleksandr Pidchosa   +2 more
doaj   +1 more source

α₄β₁-Integrin regulates directionally persistent cell migration in response to shear flow stimulation

American Journal of Physiology-Cell Physiology, 2008
α4β1-Integrin plays a pivotal role in cell migration in vivo. This integrin has been shown to regulate the front-back polarity of migrating cells via localized inhibition of α4-integrin/paxillin binding by phosphorylation at the α4-integrin cytoplasmic tail.
Dustin A, Dikeman, Leslie A, Rivera Rosado, Troy A, Horn, Christina S, Alves, Konstantinos, Konstantopoulos, Joy T, Yang   +5 more
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Modelo de gobernanza para el uso de la inteligencia artificial en la justicia penal y sus dimensiones problemáticas

Revista Científica General José María Córdova
La incorporación de la inteligencia artificial (IA) en la justicia penal desafía el debido proceso y la igualdad ante la ley, afectando de forma especial a poblaciones vulnerables como los migrantes irregulares.
Giuseppe Kodjack VII Gangi-Guillen, Juan José Delgado-Morán, Lenny Liz-Rivas   +2 more
doaj   +1 more source

PROBLEMS OF LABOUR FORCE CUSTOMIZATION IN A MEGALOPOLIS

Вестник университета, 2020
Shortage of labour force implies making more efficient use of the existing labor potential in a megalopolis. It puts in question the determination of the actual deficiency of workforce.
O. A. Tettsoeva
doaj   +1 more source