Results 71 to 80 of about 1,656,222 (302)

MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]

open access: yes, 2013
Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Preziosi, Luigi, Scianna, Marco
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Migration Processes In Contemporary Estonia [PDF]

open access: yes, 2017
This article examines migration trends in contemporary Estonia, focusing on migrant movements, legal regulations applying to migrants and national policies dealing with migration. Estonia is a multi-ethnic country in which both immigration and emigration
Włodarska-Frykowska, Agata
core   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Managing migration: the Brazilian case [PDF]

open access: yes
The objective of this paper is to present the Brazilian migration experience and its relationship with migration management. The article is divided into three parts.
Eduardo L. G. Rios-Neto
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Integration of forced Ukrainian migrants under conditions of full-scale war: a comparative analysis of EU and Ukrainian practices

open access: yesČasopis Socìalʹno-Ekonomìčnoï Geografìï. Часопис соціально-економічної географії
The article provides a comprehensive analysis of the integration processes of Ukrainian migrants in the countries of the European Union and internally displaced persons (IDPs) in Ukraine under the conditions of a full-scale war, which has caused ...
Liudmуla Kliuchko   +2 more
doaj   +1 more source

Process migration: effects on scientific computation

open access: yesACM SIGPLAN Notices, 1988
This report describes the notion of process migration. and points out certain vulnerabilities to architectural assumptions. Computationally intensive processes, typified by scientific computations, are among the best candidates for migration. In architecturally heterogeneous systems, these processes face particular problems due to their dependence on ...
Gerald Q. Maguire Jr., Jonathan M. Smith
openaire   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Migration and Adaptation as Indicators of Social Mobility Migrants

open access: yesBehavioral Sciences, 2020
The economic and social changes in modern society have resulted in intensive and extensive migrant activity. The article contains a review of social, psychological, and gender aspects of migration from three countries of Central Asia (former Soviet ...
Svetlana Gurieva   +2 more
doaj   +1 more source

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