Results 101 to 110 of about 325,848 (294)

Skilled migration: the perspective of developing countries [PDF]

open access: yes
The authors focus on the consequences of skilled migration for developing countries. They first present new evidence on the magnitude of migration of skilled workers at the international level and then discuss its direct and indirect effects on human ...
Docquier, Frederic, Rapoport, Hillel
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Two population models with constrained migrations

open access: yes, 2012
We study two models of population with migration. We assume that we are given infinitely many islands with the same number r of resources, each individual consuming one unit of resources.
Normand, Raoul
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

"CATÓLICOS, APOSTÓLICOS Y NO-SATÁNICOS ": REPRESENTACIONES CONTEMPORÁNEAS EN MÉXICO Y CONSTRUCCIONES LOCALES (VERACRUZ) DEL CULTO A LA SANTA MUERTE.

open access: yesRevista Cultura & Religión, 2014
Este artículo, mediante un enfoque basado en un cuestionamiento de la oposición clásica entre religión institucional y religiosidad popular, propone analizar la manera en que los devotos del culto a la Santa Muerte, en interacción con los medios de ...
Kali Argyriadis
doaj  

Lorsque le contrôle des migrations prend le pas sur la sauvegarde de la vie en mer : l’émergence des frontières dans la zone de responsabilité SAR espagnole

open access: yesCriminologie
Selon les conventions internationales régissant le sauvetage en mer, les frontières maritimes ne doivent pas interférer avec les opérations de sauvetage en mer, la sauvegarde de la vie en mer étant définie comme prioritaire. Pourtant, depuis 2015 et dans
Arnaud Banos   +4 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Regional wage convergence in Spain : 1850-1930 [PDF]

open access: yes, 2002
Real wages PPP adjusted are used to analyse labour market integration in Spain. In contrast to earlier research analysing migration and nominal wages rates, our research seems to indicate that a well-integrated labour market had emerged in Spain by 1914 ...
Rosés, Joan R., Sánchez-Alonso, Blanca
core   +1 more source

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