Results 111 to 120 of about 325,848 (294)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Territorios fragmentados. Estado y comunidad indígena en el Istmo veracruzano, Emilia Velázquez Hernández

open access: yesAlteridades, 2014
Reseña del libro de  Emilia Velázquez Hernández, Territorios fragmentados. Estado y comunidad indígena en el Istmo veracruzano, Centro de Investigaciones y Estudios Superiores en Antropología Social/Publicaciones de la Casa Chata, México, 2006.  
Odile Hoffmann
doaj  

ETAT DES LIEUX DE L’ENSEIGNEMENT EN FRANCAIS EN REPUBLIQUE DEMOCRATIQUE DU CONGO : ECUEILS ET OPPORTUNITES

open access: yesRegard lucide, 2023
Dans un contexte marqué par la prolifération des crises qui résultent principalement du mauvais fonctionnement des dispositifs de régulation, cet article met en perspective de nouvelles solutions dont la trame de fond est la réorientation de la ...
SOLO LOLA BIENVENU
doaj  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Prácticas devocionales y construcción del espacio en la movilidad

open access: yesAlteridades, 2014
El trabajo observa cómo las prácticas religiosas se acomodan al espacio-tiempo de la movilidad, en el contexto de la migración entre México y Estados Unidos.
Frida Calderón Bon, Olga Odgers Ortiz
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

People of the Road: the Role of Ethnic Origin in Migration Decisions. A Study of Slovak Roma Asylum-Seekers in the Czech Republic in 1998-2006 [PDF]

open access: yes
This paper deals with the analyzing possible inter-dependence between ethnical origin and migration. Evidence suggests that ethnicity might impersonalize strong cultural and socio-demographical characteristics that should not be omitted when accessing ...
Wadim Strielkowski
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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