Results 41 to 50 of about 325,848 (294)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A Preliminary Assessment of Tidal Flooding along the New Hampshire Coast: Past, Present and Future [PDF]

, 2001
This report presents the results of a preliminary study that examines several critical coastal issues for New Hampshire including sea level fluctuations (past, present and future), shoreline migrations, and tidal flooding. Included are: 1) an analysis of
Adams, Jamie R., Ward, Larry G.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Haití en las Américas. Puntos de quiebre en las políticas migratorias y movilidades haitianas en el continente (2010-2023)

Cuadernos Inter.c.a.mbio sobre Centroamérica y el Caribe
En este trabajo analizo el panorama regional que favoreció el despliegue de nuevas movilidades haitianas en las Américas a partir del año 2010 y hasta el año 2023 con la implementación de la aplicación digital (la CBP One) del Departamento ...
Catherine Bourgeois
doaj   +1 more source

Les ambivalences de l’État social-sécuritaire

Lien Social et Politiques, 2007
L’article envisage le changement du paradigme des politiques publiques liées à l’insécurité en milieu urbain. À l’encontre de ceux qui voient l’émergence d’un État pénal se substituant à l’État social, l’article soutient, à partir de l’étude de la ...
Andrea Rea
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Letter Migrations between Words in Reading Aloud Can Result either from an Impairment in Orthographic Input or in Phonological Output

Brain Sciences, 2023
Letter migrations between words in reading aloud (e.g., reading “cane love” as “lane love” or “lane cove”) are known to result from a deficit in the visual-orthographic analysis and characterize attentional dyslexia.
Liora Toledano, Naama Friedmann
doaj   +1 more source

Demography of sea lamprey (Petromyzon marinus) ammocoete populations in relation to potential spawning-migration obstructions [PDF]

, 2017
Copyright © 2017 John Wiley & Sons, Ltd. Recent advances in the understanding of lamprey migrations have led to concerns over the impacts of obstructions on the demography of many species. This study investigated sea lamprey (Petromyzon marinus) larvae
Bolland, J. D., Cowx, I. G., Harvey, J. P., Noble, R. A. A., Nunn, A. D., Taylor, R. J.   +5 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Migration, urban population growth and regional disparity in China [PDF]

The main objective of this paper is to study the determinants of city population growth in China during the 1990s', as well as the determinants of migrations towards cities, which constitutes the main source of urban population growth in this period.
Mary-Françoise Renard, Nong Zhu, Zelai Xu   +2 more
core   +3 more sources