Results 121 to 130 of about 779,313 (392)
Effect of ApoE E4 Variant on Progression from Mild Cognitive Impairment to Alzheimer’s Disease [PDF]
, 2016 Alzheimer’s disease is a very prevalent and fatal disorder in older adults, and Mild Cognitive Impairment is often seen as a precursor to Alzheimer’s disease.
Taylor, Brad P
core +1 more source
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan +7 more
wiley +1 more source
Frontiers in NeurologyBackgroundIn recent years, the problem of cognitive impairment in the elderly has become increasingly prominent. Understanding the research trend of influencing factors of mild cognitive impairment, and provide reference for medical staff to early ...
Lei Yang +4 more
doaj +1 more source
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita +7 more
wiley +1 more source
Health Services and Delivery Research, 2020 Background: People aged ≥ 50 years constitute the fastest-growing group in the prison population of England and Wales. This population has complex health and social care needs.
Katrina Forsyth +23 more
doaj +1 more source
HOPE: Hybrid-granularity Ordinal Prototype Learning for Progression Prediction of Mild Cognitive Impairment [PDF]
IEEE Journal of Biomedical and Health Informatics, 2024Mild cognitive impairment (MCI) is often at high risk of progression to Alzheimer's disease (AD). Existing works to identify the progressive MCI (pMCI) typically require MCI subtype labels, pMCI vs. stable MCI (sMCI), determined by whether or not an MCI patient will progress to AD after a long follow-up.
arxiv +1 more source
JAMA Network Open, 2019 Key Points Question Is alcohol consumption associated with the risk of dementia and cognitive decline in older adults with or without mild cognitive impairment?
M. Koch +11 more
semanticscholar +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
Semantic Function in Mild Cognitive Impairment
Frontiers in Psychology, 2020 It is well-established that semantic deficits are observed in mild cognitive impairment (MCI). However, the extent of impairment in different aspects of semantic function remains unclear, and may be influenced by the tasks used to assess performance.
Vanessa Taler +6 more
doaj +1 more source
Neuroticism, depression, and anxiety traits exacerbate the state of cognitive impairment and hippocampal vulnerability to Alzheimer's disease [PDF]
, 2017 Certain personality traits are associated with higher risk of Alzheimer's disease, similar to cognitive impairment. The identification of biological markers associated with personality in mild cognitive impairment could advance the early detection of ...
Donati, Alessia +8 more
core +2 more sources