Results 111 to 120 of about 2,881,091 (302)

A Cognitive Electrophysiological Signature Differentiates Amnestic Mild Cognitive Impairment from Normal Aging [PDF]

, 2017
Background: Noninvasive and effective biomarkers for early detection of amnestic mild cognitive impairment (aMCI) before measurable changes in behavioral performance remain scarce.
Munro, Nancy B., Abner, Erin L., Kryscio, Richard J., Kryscio, Richard, Li, Juan, Jicha, Gregory A., Broster, Lucas S., Schmitt, Frederick A., Abner, Erin, Smith, Charles D., Jiang, Yang   +10 more
core   +1 more source

Bibliometric analysis of research trends on factors affecting older adults with mild cognitive impairment

Frontiers in Neurology
BackgroundIn recent years, the problem of cognitive impairment in the elderly has become increasingly prominent. Understanding the research trend of influencing factors of mild cognitive impairment, and provide reference for medical staff to early ...
Lei Yang, Rushi Yang, Bo Wang, Tiantian Liu, Ziyi Wang   +4 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Considering the base rates of low performance in cognitively healthy older adults improves the accuracy to identify neurocognitive impairment with the Consortium to Establish a Registry for Alzheimer's Disease-Neuropsychological Assessment Battery (CERAD-NAB) [PDF]

, 2015
It is common for some healthy older adults to obtain low test scores when a battery of neuropsychological tests is administered, which increases the risk of the clinician misdiagnosing cognitive impairment.
Grant L. Iverson, Panagiota Mistridis, Klaus Willmes, Simone C. Egli, Manfred Berres, Iverson, Grant L., Berres, Manfred, Monsch, Andreas U., Egli, Simone C., Welsh-Bohmer, Kathleen A., Andreas U. Monsch, Willmes, Klaus, Iverson, Grant, Mistridis, Panagiota, Kathleen A. Welsh-Bohmer   +14 more
core   +1 more source

The executive function in the elderly with mild cognitive impairment

, 2004
Porteus Maze Test, Trail Making Test, Stroop color-word test, Negative Priming, Go-No/Go test, and Verbal fluency test were used for exploring the processing speed and executive function of 30 the elderly with Mild Cognitive Impairment (MCI) and 30 ...
Y. M. Zhang, Z. Zhang, B. X. Han
core   +1 more source

Pharmacotherapy of mild cognitive impairment

Dialogues in Clinical Neuroscience, 2004
Amnestic mild cognitive impairment (MCI) can be considered as a state with a high risk of developing Alzheimer's disease within 5 years, or as a prodromal stage of this condition. Randomized clinical trials comparing the acetylcholinesterase inhibitor donepezil with placebo have shown some symptomatic benefit on (i) cognition in one short-term (6-month)
openaire   +3 more sources

Epidemiology of Mild Cognitive Impairment in Brazil [PDF]

Dementia & Neuropsychologia, 2013
ABSTRACT With the worldwide increase in longevity and rising prevalence of cognitive disorders in the aged population, efforts have been made to characterize mild cognitive impairment (MCI) and its prevalence and/or incidence in a number of countries, given MCI may be a pre-dementia phase of degenerative conditions.
openaire   +5 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Cortical sources of resting state EEG rhythms are sensitive to the progression of early stage Alzheimer's disease [PDF]

, 2013
Cortical sources of resting state electroencephalographic (EEG) rhythms are abnormal in subjects with Alzheimer's disease (AD). Here we tested the hypothesis that these sources are also sensitive to the progression of early stage AD over the course of ...
Nicola Marzano, Lizio, Roberta, Montella, Patrizia, F. Nobili, Giovanni B Frisoni, Vernieri, Fabrizio, De Salvo S, NOBILI, FLAVIO MARIANO, G. Tedeschi, Vernieri F, Nobili, Flavio, S. De Salvo, Frisoni GB, J. C. Richardson, De Salvo, Simona, P. M. Rossini, F. Vernieri, Babiloni C, Salvatore E, G. Rodriguez, Frisoni, Giovanni B., Paolo M. Rossini, A. Soricelli, Guido Rodriguez, Jill C. Richardson, G. B. Frisoni, Fabrizio Vernieri, C. Del Percio, Mundi C, Babiloni, Claudio, Salvatore, Elena, S. Marino, Del Percio C, Rossini P.M., Soricelli, Andrea, Marzano N, E. Salvatore, Elena Salvatore, Rossini, Paolo Maria, Lizio R, F. Ursini, Mundi, Ciro, Roberta Lizio, Silvia Marino, Tedeschi, Gioacchino, Richardson, Jill C., Montella P, R. Ferri, Flavio Nobili, Rodriguez G, Rossini PM, C. Mundi, Francesca Ursini, Filomena I.I. Cosentino, Gioacchino Tedeschi, Soricelli A, Tedeschi G, Raffaele Ferri, Cosentino, Filomena I. I., Ferri R, Richardson JC, F. I. I. Cosentino, Patrizia Montella, Marzano, Nicola, Del Percio, Claudio, Marino S, Claudio Del Percio, Rossini, Paolo M., Andrea Soricelli, P. Montella, Ferri, Raffaele, Marino, Silvia, Ursini, Francesca, Nobili F, N. Marzano, Cosentino, Filomena I.I., Rodriguez, Guido, Ursini F, Claudio Babiloni, Cosentino FI, Simona De Salvo, Ciro Mundi, Frisoni, Giovanni B   +82 more
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source