Results 91 to 100 of about 483,719 (279)

Threshold effects of insulin resistance on cognitive function in coronary heart disease: the non-linear diagnostic value of the triglyceride-glucose index

Frontiers in Cardiovascular Medicine
BackgroundInsulin resistance contributes to cognitive dysfunction in patients with coronary heart disease (CHD). We examined the dose-response relationship between the triglyceride-glucose (TyG) index and cognitive status in this population.MethodsWe ...
Shun Zhao, Yejing Zhao, Xiaohong Wu, Changjiang Li, Hongyu Peng   +4 more
doaj   +1 more source

Multimodal MRI-based Imputation of the Aβ+ in Early Mild Cognitive Impairment. [PDF]

, 2014
ObjectiveTo identify brain atrophy from structural-MRI and cerebral blood flow(CBF) patterns from arterial spin labeling perfusion-MRI that are best predictors of the Aβ-burden, measured as composite 18F-AV45-PET uptake, in individuals with early mild ...
Joshi, Sarang, the Alzheimer’s Disease Neuroimaging Initiative, Tosun, Duygu, Weiner, Michael W   +3 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

The effects of healthy aging, amnestic mild cognitive impairment, and Alzheimer's disease on recollection, familiarity and false recognition, estimated by an associative process-dissociation recognition procedure [PDF]

, 2016
Given the uneven experimental results in the literature regarding whether or not familiarity declines with healthy aging and cognitive impairment, we compare four samples (healthy young people, healthy older people, older people with amnestic mild ...
Abe, Alfonso Pitarque, Algarabel, Alicia Sales, Balota, Buchler, Budson, Budson, Budson, Budson, Cohn, Dubois, Dubois, Dunn, Encar Satorres, Folstein, Gallo, Gallo, Hildebrant, Hildebrant, Hudon, Joaquín Escudero, Juan C. Meléndez, Kilb, Koen, Koen, Light, McCabe, Morris, Norman, Old, Petersen, Petersen, Pitarque, Pitarque, Prull, Radloff, Rey, Reyna, Rhodes, Salvador Algarabel, Schacter, Schoemaker, Stern, Teresa Mayordomo, Tussing, van Halteren-van Tilborg, Watson, Wechsler, Wechsler, Wixted, Wixted, Wolk, Wolk, Yeung, Yonelinas, Yonelinas, Yonelinas   +57 more
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Effect of emotional stimulus on response inhibition in people with mild cognitive impairment: an event-related potential study

Frontiers in Neuroscience
BackgroundA few studies are emerging to explore the issue of how aging promotes emotional response inhibition. However, there is a lack of empirical study concerning the impact of pathological cognitive impairment on emotional response inhibition.
Jing Wang, Cheng Li, Xiaohong Yu, Yue Zhao, Enfang Shan, Ying Xing, Xianwen Li   +6 more
doaj   +1 more source

The Risk of Incident Mild Cognitive Impairment and Progression to Dementia Considering Mild Cognitive Impairment Subtypes

Dementia and Geriatric Cognitive Disorders Extra, 2017
Background: It remains unclear how demographic and clinical characteristics are related to the risk of incident mild cognitive impairment (MCI) by its subtypes.
Tzeyu L. Michaud, Dejun Su, Mohammad Siahpush, Daniel L. Murman   +3 more
doaj   +1 more source

Modern aspects of diagnosis and treatment of mild cognitive impairment

Российский журнал гериатрической медицины, 2020
The study of cognitive impairments (CI) began with a more severe form- dementia, which is usually the result of a long-running pathological process. It is preceded by non-demented cognitive disorders (including mild cognitive impairment syndrome — MCI ...
A. B. Lokshina
doaj   +1 more source

Validation of the German Revised Addenbrooke's Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer's Disease and Frontotemporal Lobar Degeneration [PDF]

, 2010
Background/Aims: The diagnostic accuracy of the German version of the revised Addenbrooke's Cognitive Examination (ACE-R) in identifying mild cognitive impairment (MCI), mild dementia in Alzheimer's disease (AD) and mild dementia in frontotemporal lobar ...
Aguilar, C. A., Alexopoulos, P., Danek, Adrian, Diehl-Schmid, J., Ebert, A., Foerstl, H., Gourzis, P., Kneib, T., Kornhuber, J., Kurz, A., Natale, B., Perneczky, R., Richter-Schmidinger, T., Schoell, E., Weih, M.   +14 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source