Results 81 to 90 of about 483,719 (279)

Perceived experiences of adults with mild cognitive impairment: a qualitative study

BMC Psychology
Introduction Increasing attention is being paid to preventing the progression of mild cognitive impairment and dementia. Today, there is a growing emphasis on listening to the “voice” of people with mild cognitive impairment to ensure patient-centered ...
Poursoleiman Leila, Rooddehghan Zahra, Bahramnezhad Fatemeh, Shafiee Sabet Mahdi, Dehghan Nayeri Nahid   +4 more
doaj   +1 more source

Souvenaid in the Management of Mild Cognitive Impairment: An Expert Consensus Opinion [PDF]

, 2019
Background Mild cognitive impairment (MCI) among an aging global population is a growing challenge for healthcare providers and payers. In many cases, MCI is an ominous portent for dementia.
Bertolucci, Paulo, Cappa, Stefano, Chen, Christopher, Chu, Leung-Wing, Cummings, Jeffrey, Engelborghs, Sebastiaan, Garcia-Ribas, Guillermo, Manzano, Sagrario, McGuinness, Bernadette, Mok, Vincent, Passmore, Peter, Woodward, Michael   +11 more
core   +3 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study

Contemporary Clinical Trials Communications, 2019
Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical
Juleen Rodakowski, Katlyn W. Golias, Charles F. Reynolds, III, Meryl A. Butters, Oscar L. Lopez, Mary Amanda Dew, Elizabeth R. Skidmore   +6 more
doaj   +1 more source

Serum vitamin D in patients with mild cognitive impairment and Alzheimer's disease [PDF]

, 2018
Objectives: To determine the relevance of Mini-Mental State Examination (MMSE), serum 25-hydroxyvitamin D (25(OH)D3), and 1,25(OH)2D3 concentrations to mild cognitive impairment (MCI) and various stages of Alzheimer's disease (AD). Materials and Methods:
Bölükbaşı Hatip, Funda Fatma, Hatip-Al-Khatib, I., Matsunaga, Y., Ouma, S., Suenaga, M., Tsuboi, Y.   +5 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

The Greek Version of the Mild Behavioral Impairment Checklist (MBI-C): Psychometric Properties in Mild Cognitive Impairment Due to Alzheimer’s Disease

Brain Sciences
Background/Objectives: Mild behavioral impairment (MBI) is an early marker of Alzheimer’s disease (AD) and other neurodegenerative diseases, often preceding cognitive decline. The MBI Checklist (MBI-C) is a 34-item tool designed to detect MBI. This study
Efthalia Angelopoulou, Evangelia Stanitsa, Maria Hatzopoulou, Akylina Despoti, Niki Tsinia, Vasiliki Kamtsadeli, Marina Papadogiani, Vasilis Kyriakidis, Sokratis Papageorgiou, John D. Papatriantafyllou   +9 more
doaj   +1 more source

Tau and atrophy: domain-specific relationships with cognition. [PDF]

, 2019
BackgroundLate-onset Alzheimer's disease (AD) is characterized by primary memory impairment, which then progresses towards severe deficits across cognitive domains.
Alzheimer’s Disease Neuroimaging Initiative, Banks, Sarah J, Brewer, James B, Dale, Anders M, Digma, Leonardino A, Madsen, John R, Reas, Emilie T   +6 more
core  

Onset of Mild Cognitive Impairment in Parkinson Disease [PDF]

, 2016
Objective: Characterize the onset and timing of cognitive decline in Parkinson disease (PD) from the first recognizable stage of cognitively symptomatic PD-mild cognitive impairment (PD-MCI) to PD dementia (PDD).
Barton, Biundo, Botwinick, Broeders, Cholerton, Cudeck, Dubois, Duncombe, Emre, Galvin, Galvin, Geurtsen, Goldman, Goldman, Hughes, Jack, Johnson, Johnson, Johnson, Lippa, Litvan, Marinelli, Marinelli, Morris, Muslimovic, Muslimovic, Pate, Petersen, Price, Reid, Slate, Stewart, Troncoso, Wang, Yarnall   +34 more
core   +2 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source