Results 121 to 130 of about 249,115 (256)

Perception of facial trustworthiness in mild cognitive impairment. [PDF]

J Alzheimers Dis
Granadeiro M, Garcia-Marques L, Torrado M, Martins IP.   +3 more
europepmc   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Structural Volumetric Alterations in Parkinson's Disease With Mild Cognitive Impairment. [PDF]

Brain Behav
Hu J, Lei P, Zhang J, Wu Q, Zhang Z, Zhu X, Li B.   +6 more
europepmc   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

A sensorimotor function construct to assess mild cognitive impairment risk. [PDF]

Alzheimers Dement
Wanigatunga AA, Wang H, Huang D, Davoudi A, Dougherty RJ, Tian Q, Deal JA, Abraham AG, Simonsick EM, Gross AL, Resnick SM, Ferrucci L, Schrack JA.   +12 more
europepmc   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Subjective cognition trajectories, Alzheimer biomarkers, and incident mild cognitive impairment. [PDF]

J Prev Alzheimers Dis
Kuhn E, Kleineidam L, Stark M, Peters O, Hellmann-Regen J, Preis L, Gref D, Priller J, Spruth EJ, Gemenetzi M, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Hansen N, Rostamzadeh A, Düzel E, Glanz W, Incesoy E, Buerger K, Janowitz D, Stöcklein S, Perneczky R, Rauchmann BS, Teipel SJ, Kilimann I, Laske C, Sodenkamp S, Spottke A, Kronmüller M, Roeske S, Brosseron F, Ramirez A, Synofzik M, Schmid MC, Jessen F, Wagner M, Alzheimer’s Disease Neuroimaging Initiative, DELCODE study group.   +38 more
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Dyadic coping in couples experiencing mild cognitive impairment. [PDF]

Int J Clin Health Psychol
Virta-Steel C, Carriere LJ, Locke DE, Shandera-Ochsner AL, Cuc A, Chandler MJ.   +5 more
europepmc   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source