Results 121 to 130 of about 284,848 (306)

Screening for mild cognitive impairment in patients with cardiovascular risk factors

open access: yes, 2017
Teodora Yaneva-Sirakova,1 Latchezar Traykov,2 Julia Petrova,2 Ivan Gruev,3 Dobrin Vassilev1 1Department of Internal Medicine, Cardiology Clinic, 2Department of Neurology, Neurology Clinic, Medical University Sofia, 3Cardiology Clinic, National Transport
Traykov L   +4 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Mild cognitive impairment and its management in older people

open access: yes, 2015
Sima Ataollahi Eshkoor, Tengku Aizan Hamid, Chan Yoke Mun, Chee Kyun Ng Institute of Gerontology, Universiti Putra Malaysia, Selangor, Malaysia Abstract: Mild cognitive impairment (MCI) is a common condition in the elderly.
Eshkoor SA, Ng CK, Hamid TA, Mun CY
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Evolving methods to combine cognitive and physical training for individuals with mild cognitive impairment: study protocol for a randomized controlled study

open access: yes, 2017
Background: Nonpharmacologic interventions, such as cognitive training or physical exercise, are effective in improving cognitive functions for older adults with mild cognitive impairment (MCI).
李亞芸   +1 more
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

The executive function in the elderly with mild cognitive impairment

open access: yes, 2004
Porteus Maze Test, Trail Making Test, Stroop color-word test, Negative Priming, Go-No/Go test, and Verbal fluency test were used for exploring the processing speed and executive function of 30 the elderly with Mild Cognitive Impairment (MCI) and 30 ...
Y. M. Zhang, Z. Zhang, B. X. Han
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Impact of vascular diseases on the progression of mild cognitive impairment to Alzheimer’s disease

open access: yes, 2015
Introduction: Mild cognitive impairment does not meet the criteria for the diagnosis of dementia, but reaching this diagnosis raises concern about the future state of a patient due to the possibility of the conversion to Alzheimer’s disease.
Maria Barcikowska   +3 more
core   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier   +3 more
wiley   +1 more source

Prevalence of Pain on Admission by Level of Cognitive Impairment in Nursing Homes

open access: yesJournal of Pain Research, 2020
Catherine E Dube, Reynolds A Morrison, Deborah S Mack, Bill M Jesdale, Anthony P Nunes, Shao-Hsien Liu, Kate L Lapane Division of Epidemiology, Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School ...
Dube CE   +6 more
doaj  

Cognitive and brain function in adults with Type 1 diabetes mellitus : is there evidence of accelerated ageing?

open access: yes, 2013
The physical complications of Type 1 diabetes mellitus (T1DM) have been understood as an accelerated ageing process (Morley, 2008). Do people with T1DM also experience accelerated cognitive and brain ageing?
Johnston, Harriet N.
core  

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