Results 131 to 140 of about 542,808 (329)

Molecular imaging of serotonin degeneration in mild cognitive impairment

Neurobiology of Disease, 2017
Neuropathological and neuroimaging studies have consistently demonstrated degeneration of monoamine systems, especially the serotonin system, in normal aging and Alzheimer's disease. The evidence for degeneration of the serotonin system in mild cognitive
Gwenn S. Smith, Frederick S. Barrett, Jin Hui Joo, Najlla Nassery, Alena Savonenko, Devin J. Sodums, Christopher M. Marano, Cynthia A. Munro, Jason Brandt, Michael A. Kraut, Yun Zhou, Dean F. Wong, Clifford I. Workman   +12 more
doaj  

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Mild Cognitive Impairment in the Population and Physical Health: Data on 1,435 Individuals Aged 75 to 95

, 2000
Giovanni B. Frisoni, Laura Fratiglioni, Johan Fastbom, Zhenyu Guo, Matti Viitanen, Bengt Winblad   +5 more
openalex   +1 more source

Increased Risk of Cognitive Impairment 3 Months After Mild to Moderate First-Ever Stroke [PDF]

, 2003
Velandai Srikanth, Amanda G. Thrift, Michael M. Saling, Jacqueline F. I. Anderson, Helen M. Dewey, Richard Macdonell, Geoffrey A. Donnan   +6 more
openalex   +1 more source

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Movement Disorders, 2012
I. Litvan, J. Goldman, A. Tröster, B. Schmand, D. Weintraub, R. Petersen, B. Mollenhauer, C. Adler, K. Marder, C. Williams-Gray, D. Aarsland, J. Kulisevsky, M. Rodriguez-Oroz, D. Burn, R. Barker, M. Emre   +15 more
semanticscholar   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Patterns of Factors in the National Institute on Aging Health Disparities Research Framework Domains and Mild Cognitive Impairment Risk

AJPM Focus
Introduction: Alzheimer's disease and related dementias are public health and social care challenges. This study used the National Institute on Aging Health Disparities Research Framework to organize potential cognitive impairment risk factors.
Maria Vassilaki, MD, PhD, Jeremiah A. Aakre, MPH, Timothy G. Lesnick, MS, Walter K. Kremers, PhD, Jonathan Graff-Radford, MD, David S. Knopman, MD, Thomas H. Mosley, PhD, B. Gwen Windham, MD, MHS, Michael E. Griswold, PhD, Yonas E. Geda, MD, MSc, Val J. Lowe, MD, Clifford R. Jack, Jr., MD, Ronald C. Petersen, MD, PhD, Prashanthi Vemuri, PhD   +13 more
doaj  

Prediction of Progression in Patients with Mild Cognitive Impairment Using IMP-SPECT.

, 2000
Nobuyuki Okamura, Mitsutoshi Shinkawa, Hiroyuki Arai, Toshifumi Matsui, Kazushi Nakajo, Masahiro Maruyama, Xia Hu, Hidetada Sasaki   +7 more
openalex   +2 more sources

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

Advanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

Practice guideline update summary: Mild cognitive impairment

Neurology, 2018
R. Petersen, Oscar Lopez, M. Armstrong, Thomas S. D. Getchius, M. Ganguli, D. Gloss, G. Gronseth, D. Marson, T. Pringsheim, G. Day, M. Sager, James C. Stevens, A. Rae-Grant   +12 more
semanticscholar   +1 more source