Cognitive Impairment Precedes and Predicts Functional Impairment in Mild Alzheimer’s Disease [PDF]
Background: The temporal relationship of cognitive deficit and functional impairment in Alzheimer’s disease (AD) is not well characterized. Recent analyses suggest cognitive decline predicts subsequent functional decline throughout AD progression ...
Baoguang Han+11 more
core +1 more source
Background: The spectrum of early Alzheimer's disease (AD) is thought to include subjective cognitive impairment, early mild cognitive impairment (eMCI), and late mild cognitive impairment (lMCI).
Wenwen Xu+9 more
doaj +1 more source
Does Physical Activity Influence Semantic Memory Activation in Amnestic Mild Cognitive Impairment? [PDF]
The effect of physical activity (PA) on functional brain activation for semantic memory in amnestic mild cognitive impairment (aMCI) was examined using event-related functional magnetic resonance imaging during fame discrimination.
Antuono, Piero+10 more
core +2 more sources
Interaction between personality traits and cerebrospinal fluid biomarkers of Alzheimer's disease pathology modulates cognitive performance. [PDF]
During adulthood, personality characteristics may contribute to the individual capacity to compensate the impact of developing cerebral Alzheimer's disease (AD) pathology on cognitive impairment in later life.
Antonietti, J.P.+5 more
core +3 more sources
Onset of Mild Cognitive Impairment in Parkinson Disease [PDF]
Objective: Characterize the onset and timing of cognitive decline in Parkinson disease (PD) from the first recognizable stage of cognitively symptomatic PD-mild cognitive impairment (PD-MCI) to PD dementia (PDD).
Barton+34 more
core +2 more sources
Cognitive deficits are common in Parkinson’s disease. Previous cross-sectional research has demonstrated a link between cognitive impairments and fronto-striatal dopaminergic dysmodulation. However, longitudinal studies that link disease progression with
Urban eEkman+6 more
doaj +1 more source
Mild behavioral impairment in Parkinson's disease: Data from the Parkinson's disease cognitive impairment study (PACOS) [PDF]
Neuropsychiatric symptoms (NPS) have been frequently described in Parkinson's disease (PD), even in the earliest stages of the disease. Recently the construct of mild behavioral impairment (MBI) has been proposed as an at-risk state for incident ...
Baschi R.+7 more
core +1 more source
Determinants of Activity Levels in African Americans With Mild Cognitive Impairment. [PDF]
Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and ...
Casten, PhD, Robin J.+2 more
core +2 more sources
A Pilot Study: The Beneficial Effects of Combined Statin-exercise Therapy on Cognitive Function in Patients with Coronary Artery Disease and Mild Cognitive Decline. [PDF]
Objective Hypercholesterolemia, a risk factor in cognitive impairment, can be treated with statins. However, cognitive decline associated with "statins" (HMG-CoA reductase inhibitors) is a clinical concern.
Hamada, Mari+10 more
core +1 more source
Patients with liver disease are prone to various cognitive impairments. It is undeniable that cognitive impairment is often regulated by both the nervous system and the immune system.
Tianning Sun+5 more
doaj +1 more source