Results 41 to 50 of about 249,115 (256)

Cognitive function in patients undergoing cystectomy for bladder cancer – results from a prospective observational study

Therapeutic Advances in Urology, 2022
Background: Impaired cognitive function of bladder cancer patients plays a role in coping with the kind of urinary diversion and may impact perioperative morbidity. In this study we therefore aimed to assess the prevalence of mild cognitive impairment in
Camilla M. Grunewald, Vera Feldmeier, Tillmann Supprian, Peter Albers, Markus Giessing, Günter Niegisch   +5 more
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

The Greek Version of the Mild Behavioral Impairment Checklist (MBI-C): Psychometric Properties in Mild Cognitive Impairment Due to Alzheimer’s Disease

Brain Sciences
Background/Objectives: Mild behavioral impairment (MBI) is an early marker of Alzheimer’s disease (AD) and other neurodegenerative diseases, often preceding cognitive decline. The MBI Checklist (MBI-C) is a 34-item tool designed to detect MBI. This study
Efthalia Angelopoulou, Evangelia Stanitsa, Maria Hatzopoulou, Akylina Despoti, Niki Tsinia, Vasiliki Kamtsadeli, Marina Papadogiani, Vasilis Kyriakidis, Sokratis Papageorgiou, John D. Papatriantafyllou   +9 more
doaj   +1 more source

Sensitive Measures of Cognition in Mild Cognitive Impairment

Journal of Alzheimer's Disease, 2020
Background: Sensitive measures of cognition are needed in preclinical and prodromal Alzheimer’s disease (AD) to track cognitive change and evaluate potential interventions. Neurofibrillary tangle pathology in AD is first observed in Brodmann Area 35 (BA35), the medial portion of the perirhinal cortex.
Nathaniel Klooster, Stacey Humphries, Eileen R. Cardillo, Franziska Hartung, Long Xie, Sandhitsu Das, Paul Yushkevich, Arun Pilania, Jieqiong Wang, David Wolk, Anjan Chatterjee   +10 more
openaire   +4 more sources

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Perceived experiences of adults with mild cognitive impairment: a qualitative study

BMC Psychology
Introduction Increasing attention is being paid to preventing the progression of mild cognitive impairment and dementia. Today, there is a growing emphasis on listening to the “voice” of people with mild cognitive impairment to ensure patient-centered ...
Poursoleiman Leila, Rooddehghan Zahra, Bahramnezhad Fatemeh, Shafiee Sabet Mahdi, Dehghan Nayeri Nahid   +4 more
doaj   +1 more source

Mild Cognitive Impairment: A Systematic Review [PDF]

Journal of Alzheimer's Disease, 2007
MCI is a nosological entity proposed as an intermediate state between normal aging and dementia. The syndrome can be divided into two broad subtypes: amnestic MCI (aMCI) characterized by reduced memory, and non-amnestic MCI (naMCI) in which other cognitive functions rather than memory are mostly impaired.
Mariani E., Monastero R., Mecocci P.
openaire   +4 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Cognitive and behavioral impairment in mild hyperphenylalaninemia [PDF]

The Turkish Journal of Pediatrics, 2018
As elevated phenylalanine (Phe) is detrimental to brain functions, determining a safe upper limit of blood Phe is important for initiation of treatment plans and setting Phe targets in hyperphenlalaninemic patients. It is accepted that Phe levels below 360 μmol/L does not impair brain function and hence does not require treatment.
Evinc, S. Gulin, Pektas, Emine, Foto-Ozdemir, Dilsad, Yildiz, Yilmaz, Karaboncuk, Yamac, Bilginer-Gurbuz, Berrak, Dursun, Ali, Tokatli, Aysegul, Coskun, Turgay, Oktem, Ferhunde, Sivri, H. Serap   +10 more
openaire   +4 more sources

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source