Results 41 to 50 of about 284,848 (306)

Psychological well-being in individuals with mild cognitive impairment

, 2014
Objectives: Cognitive impairments associated with aging and dementia are major sources of burden, deterioration in life quality, and reduced psychological well-being (PWB).
Valenzuela, M ; https://orcid.org/, Sachdev ; https://orcid.org/, Fiatarone Singh, M, Gates, N ; https://orcid.org/   +3 more
core   +2 more sources

Dual task impairments in vascular dementia [PDF]

, 2010
Several studies have shown that people with Alzheimer's disease (AD) demonstrate difficulties in doing two things at once or 'dual-tasking' and that this dual task impairment is insensitive to normal ageing, chronic depression or prodromal conditions ...
Della Sala, Sergio, Sergio Della Sala, Foley, JA, Kate Inasaridze, Inasaridze, K., Logie, R. H., Robert H. Logie, Sala, SD, Foley, Jennifer, Inasaridze, K, Jennifer A. Foley, Logie, RH   +11 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Regulation of mild cognitive impairment associated with liver disease by humoral factors derived from the gastrointestinal tract and MRI research progress: a literature review

Frontiers in Neuroscience, 2023
Patients with liver disease are prone to various cognitive impairments. It is undeniable that cognitive impairment is often regulated by both the nervous system and the immune system.
Tianning Sun, Maohui Feng, Anne Manyande, Hongbing Xiang, Jun Xiong, Zhigang He   +5 more
doaj   +1 more source

Mild Cognitive Impairment and Diagnostic Possibilities of Early Testing

, 2023
The mental state of patients is an important aspect that affects physical health and the quality of life. Mild Cognitive impairment (MCI) is associated with an increased risk of developing Alzheimer’s disease (AD).
Jacob, Chris Mariam
core  

Resting state cortical electroencephalographic rhythms in covert hepatic encephalopathy and Alzheimer's disease [PDF]

, 2013
Patients suffering from prodromal (i.e., amnestic mild cognitive impairment, aMCI) and overt Alzheimer's disease (AD) show abnormal cortical sources of resting state electroencephalographic (EEG) rhythms.
Nicola Marzano, Lizio, Roberta, Giovanni B. Frisoni, Serviddio, Gaetano, Vecchio F, Chini G, Piero Amodio, Frisoni GB, P. M. Rossini, Schiff S, Babiloni C, F. Vecchio, Frisoni, Giovanni B., Amodio P., Paolo M. Rossini, A. Soricelli, Serviddio G, G. B. Frisoni, C. Del Percio, Babiloni, Claudio, Chini, Giorgia, Del Percio C, Soricelli, Andrea, Marzano N, P. Amodio, Rossini, Paolo Maria, Lizio R, Roberta Lizio, Sami Schiff, Montagnese, Sara, S. Montagnese, S. Schiff, Fabrizio Vecchio, Rossini PM, Schiff, Sami, Soricelli A, Vecchio, Fabrizio, Marzano, Nicola, Del Percio, Claudio, Claudio Del Percio, G. Chini, Rossini, Paolo M., G. Serviddio, Andrea Soricelli, N. Marzano, Gaetano Serviddio, Sara Montagnese, Amodio, Piero, Claudio Babiloni, Giorgia Chini, Montagnese S   +50 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]

, 2012
Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
Bartlett, Jonathan W, Macdonald, Kate E, Leung, Kelvin K, ADNI investigators, Barnes, Josephine, Ourselin, Sebastien   +5 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source