Results 31 to 40 of about 284,848 (306)

Altered Functional Connectivity of the Basal Nucleus of Meynert in Subjective Cognitive Impairment, Early Mild Cognitive Impairment, and Late Mild Cognitive Impairment

Frontiers in Aging Neuroscience, 2021
Background: The spectrum of early Alzheimer's disease (AD) is thought to include subjective cognitive impairment, early mild cognitive impairment (eMCI), and late mild cognitive impairment (lMCI).
Wenwen Xu, Jiang Rao, Yu Song, Shanshan Chen, Chen Xue, Guanjie Hu, Guanjie Hu, Xingjian Lin, Jiu Chen, Jiu Chen   +9 more
doaj   +1 more source

Differences between memoryencoding and retrieval failure in mild cognitive impairment: results from quantitative electroencephalography and magnetic resonance volumetry [PDF]

, 2021
Background The memory impairments in mild cognitive impairment (MCI) can be classified into encoding (EF) and retrieval (RF) failure, which can be affected by underlying pathomechanism.
Kang, Dong W, Youn, Young C, Han, Su-Hyun, Jeong, Ho T, Yeo, Soeun, Kim, SangYun, Pyun, Jung-Min, Kang, Seung W   +7 more
core   +1 more source

Neurofilament light as a biomarker of axonal degeneration in patients with mild cognitive impairment and Alzheimer’s disease

Journal of Integrative Neuroscience, 2021
Cerebrospinal fluid neurofilament light and plasma neurofilament light concentrations are elevated in patients with mild cognitive impairment and Alzheimer’s disease.
Yi Chen, Joseph Therriault, Jing Luo, Maowen Ba, Hua Zhang, Alzheimer’s Disease Neuroimaging Initiative   +5 more
doaj   +1 more source

Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment

, 2012
Few studies have looked at the potential of using diffusion tensor imaging (DTI) in conjunction with machine learning algorithms in order to automate the classification of healthy older subjects and subjects with mild cognitive impairment (MCI).
Lamberton, Franck, David Prvulovic, O’Neill, Desmond, Desmond O'Neill, Harald Hampel, Prvulovic David, Bartley, M., Prvulovic, D., Coughlan, T., Mazoyer, B., Lamberton, F., Collins, D.R., Bokde, Arun L W, Laurence O'Dwyer, Coughlan Tara, O'Neill, Desmond, Ewers, Michael, Bokde, A.L., O'Neill, D., Ewers, M., Mazoyer Bernard, Franck Lamberton, Collins, D. Rónán, O'Neill Desmond, Arun L W Bokde, Tara Coughlan, Bartley, Máiréad, Bokde Arun L. W., Faluyi, Y.O., Hampel Harald, D Rónán Collins, O'Dwyer Laurence, O'Dwyer, Laurence, Collins, D Rónán, Máiréad Bartley, Tanner, C., Faluyi, Yetunde O., Tanner Colby, Bartley Máiréad, O’Dwyer, Laurence, Bokde, Arun L. W., Lamberton Franck, Faluyi Yetunde O., Mazoyer, Bernard M., Mazoyer, Bernard, Hampel, Harald, Prvulovic, David, Michael Ewers, O'Dwyer, L.G., Faluyi, Yetunde O, Colby Tanner, Collins D. Rónán, Tanner, Colby, Hampel, H., Coughlan, Tara, Ewers Michael, Yetunde O Faluyi, Bernard Mazoyer   +57 more
core   +1 more source

Longitudinal changes in task-evoked brain responses in Parkinson’s disease patients with and without mild cognitive impairment

Frontiers in Neuroscience, 2014
Cognitive deficits are common in Parkinson’s disease. Previous cross-sectional research has demonstrated a link between cognitive impairments and fronto-striatal dopaminergic dysmodulation. However, longitudinal studies that link disease progression with
Urban eEkman, Johan eEriksson, Lars eForsgren, Magdalena Eriksson Domellöf, Eva eElgh, Anders eLundquist, Lars eNyberg   +6 more
doaj   +1 more source

Different patterns of white matter degeneration using multiple diffusion indices and volumetric data in mild cognitive impairment and Alzheimer patients

, 2012
Alzheimeŕs disease (AD) represents the most prevalent neurodegenerative disorder that causes cognitive decline in old age. In its early stages, AD is associated with microstructural abnormalities in white matter (WM).
Alves, Gilberto Sousa, Gilberto Sousa Alves, Felipe Sudo, Tarik Karakaya, Letice Valente, Laurence O’Dwyer, Viola Oertel-Knöchel, Engelhardt, Eliasz, David Prvulovic, Denise Moreira, Christian Knöchel, O’Dwyer, Laurence, Karakaya, Tarik, Fabian Fuβer, Carlos Eduardo Alves, Fußer, Fabian, Johannes Pantel, Laurence O'Dwyer, Valente, Letice, Jerson Laks, Prvulovic, David, Moreira, Denise, Alves, Carlos Eduardo, Alina Jurcoane, Pantel, Johannes, Oertel-Knöchel, Viola, Laks, Jerson, Eliasz Engelhardt, Sudo, Felipe, Fabian Fußer, Jurcoane, Alina, Knöchel, Christian   +31 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease [PDF]

, 2011
We recently reported that expression levels of tumor necrosis factor (TNF) receptors, TNFR1 and TNFR2, are significantly changed in the brains and cerebral spinal cerebral fluid (CSF) with Alzheimer's disease (AD).
Blennow, Kaj,, Shen, Yong, Hampel, Harald, Rena Li, Hampel Harald, Prvulovic, David, Yong Shen, Wallin, Anders,, Jiang, Hong, David Prvulovic, Hong Jiang, Wallin, Anders, Kaj Blennow, Wallin Anders, Shen Yong, Anders Wallin, Li, Rena, Blennow Kaj, Jiang Hong, Prvulovic David, Harald Hampel, Blennow, Kaj, Li Rena   +22 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source