Background: Cognitive impairment is a disabling and underestimated consequence of multiple sclerosis (MS), with multiple determinants that are poorly understood.
Nicholas J. Snow +3 more
doaj +1 more source
Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration. [PDF]
OBJECTIVE: To quantify the regional and global cerebral atrophy rates and assess acceleration rates in healthy controls, subjects with mild cognitive impairment (MCI), and subjects with mild Alzheimer disease (AD).
Manning, Emily N +16 more
core +1 more source
Mild cognitive impairment (MCI): a historical perspective
Descriptions of dementia can be traced to antiquity. Prichard (1837) described four dementia stages and Kral (1962) described a "benign senescent forgetfulness" condition. The American Psychiatric Association's DSM-III (1980) identified an early dementia stage.
Barry, Reisberg +5 more
openaire +2 more sources
Microstate connectivity alterations in patients with early Alzheimer's disease [PDF]
Electroencephalography (EEG) microstates and brain network are altered in patients with Alzheimer's disease (AD) and discussed as potential biomarkers for AD. Microstates correspond to defined states of brain activity, and their connectivity patterns may
Andreas Monsch (3564989) +26 more
core +1 more source
Early Detection of Mild Cognitive Impairment (MCI) in Primary Care [PDF]
Mild cognitive impairment (MCI) is significantly misdiagnosed in the primary care setting due to multi-dimensional frictions and barriers associated with evaluating individuals' cognitive performance. To move toward large-scale cognitive screening, a global panel of clinicians and cognitive neuroscientists convened to elaborate on current challenges ...
Sabbagh, Marwan +13 more
openaire +3 more sources
Detecting type 2 diabetes mellitus cognitive impairment using whole-brain functional connectivity
Type 2 diabetes mellitus (T2DM) is closely linked to cognitive decline and alterations in brain structure and function. Resting-state functional magnetic resonance imaging (rs-fMRI) is used to diagnose neurodegenerative diseases, such as cognitive ...
Jinjian Wu +9 more
doaj +1 more source
(1) Background: Dementia and mild cognitive impairment (MCI) are still underdiagnosed in the general population. Impaired odor identification has been identified as an early marker of MCI and dementia.
Wolfgang Trapp +4 more
doaj +1 more source
Regional coherence evaluation in mild cognitive impairment and Alzheimer's disease based on adaptively extracted magnetoencephalogram rhythms [PDF]
This study assesses the connectivity alterations caused by Alzheimer's disease (AD) and mild cognitive impairment (MCI) in magnetoencephalogram (MEG) background activity.
Abasolo, Daniel +14 more
core +1 more source
Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting [PDF]
Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers.
Sabbagh, Marwan +13 more
openaire +3 more sources
Multiple indices of diffusion identifies white matter damage in mild cognitive impairment and Alzheimer's disease [PDF]
The study of multiple indices of diffusion, including axial (DA), radial (DR) and mean diffusion (MD), as well as fractional anisotropy (FA), enables WM damage in Alzheimer's disease (AD) to be assessed in detail.
Bartley, Máiréad +32 more
core +2 more sources

