Results 91 to 100 of about 3,751,517 (253)

Existence Results for Semilinear Differential Evolution Equations with Impulses and Delay

Cubo, 2010
In this paper, we establish sufficient conditions for the existence of mild and extremal solutions for some densely defined impulsive functional differential equations in separable Banach spaces with local and nonlocal conditions.
Nadjet Abada, Mouffak Benchohra, Hadda Hammouche   +2 more
doaj  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Local mild solutions and impulsive mild solutions for semilinear Cauchy problems involving lower Scorza-Dragoni multifunctions

, 2008
In this note we investigate in Banach spaces the existence of mild solutions for initial problems, also in presence of impulses, governed by semilinear differential inclusions where the non-linear part is a Scorza-Dragoni multifunction.
Portigiani, Francesco, Rubbioni, Paola, Cardinali, Tiziana   +2 more
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

On the regularity of mild solutions to complete higher order differential equations on Banach spaces [PDF]

Surveys in Mathematics and its Applications, 2015
For the complete higher order differential equation u(n)(t)=Σk=0n-1Aku(k)(t)+f(t), t∈ R (*) on a Banach space E, we give a new definition of mild solutions of (*). We then characterize the regular admissibility of a translation invariant subspace al M of
Nezam Iraniparast, Lan Nguyen
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Existence and Approximate Controllability for Higher-Order Hilfer Fractional Evolution Equations via Fixed-Point and Sequence Approaches

Mathematics
This study addresses the existence and approximate controllability of a type of higher-order Hilfer fractional evolution differential (HOHFED) system with time delays in Banach spaces. Using the properties of the Mittag–Leffler function, cosine families,
Marimuthu Mohan Raja, Chan-Ho Han, Kalyana Chakravarthy Veluvolu   +2 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Existence of mild solutions for a neutral fractional equation with fractional nonlocal conditions

Electronic Journal of Differential Equations, 2012
The existence of mild solutions in an appropriate space is established for a second-order abstract problem of neutral type with derivatives of non-integer order in the nonlinearity as well as in the initial conditions.
Nasser-eddine Tatar
doaj  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source