Results 171 to 180 of about 168,085 (280)

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury. [PDF]

J Biomed Sci
Ho MH, Tsai YJ, Lee YH, Hsieh YC, Yen CH, Wang JY, Burnouf T, Chen CY, Lin WC, Wang Y, Chiang YH, Hoffer BJ, Chou SY.   +12 more
europepmc   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

The Role of MRI in Debunking the Fallacy of "Mild" Traumatic Brain Injury. [PDF]

J Magn Reson Imaging
Chen X, Wright D, Chung S, Lui Y.
europepmc   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Mild Traumatic Brain Injury and Functional Amnesia: When Concussion Becomes a Gateway to Functional Cognitive Disorder. [PDF]

Brain Sci
Mavroudis I, Petridis F, Ciobica A, Papagiannopoulos S, Kazis D.   +4 more
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Persistent sleep disturbances after mild traumatic brain injury: A prospective multimodal assessment with actigraphy and hormonal biomarkers. [PDF]

Brain Spine
Paredes I, Castaño-Leon AM, Cunha Alves V, Sánchez Carabias C, Delgado-Fernandez J, Moreno LM, García-Posadas G, Maldonado Luna M, Baciu AE, Tosi L, Lagares A.   +10 more
europepmc   +1 more source

Are Mental Health Symptoms of Parents of Young People Accessing Treatment for Eating Disorders Associated With Accommodating and Enabling Behaviours?

European Eating Disorders Review, EarlyView.
ABSTRACT Background Parental and family factors influence treatment outcomes of adolescents with eating disorders (EDs), particularly in family‐based interventions. However, little is known about how parental mental health is associated with well‐established factors that influence treatment outcomes.
Daniel Wilson, Renata A. Mendes, Natalie J. Loxton, James G. Scott, Lieve Leering, Govind Krishnamorthy, Jacinda White   +6 more
wiley   +1 more source

Commentary on: exploring exercise intolerance in adult patients with persistent post-concussion symptoms after mild traumatic brain injury. [PDF]

J Rehabil Med
Jun T, Li H, Feng W.
europepmc   +1 more source