Results 21 to 30 of about 3,312,183 (259)

Diagnostic accuracy of prehospital serum S100B and GFAP in patients with mild traumatic brain injury: a prospective observational multicenter cohort study – “the PreTBI I study”

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background The biomarker serum S100 calcium-binding protein B (S100B) is used in in-hospital triage of adults with mild traumatic brain injury to rule out intracranial lesions.
Sophie-Charlott Seidenfaden, Julie Linding Kjerulff, Niels Juul, Hans Kirkegaard, Mette Fogh Møller, Anna-Marie Bloch Münster, Morten Thingemann Bøtker   +6 more
doaj   +1 more source

Structural and functional connectivity of the whole brain and subnetworks in individuals with mild traumatic brain injury: predictors of patient prognosis

Neural Regeneration Research
Patients with mild traumatic brain injury have a diverse clinical presentation, and the underlying pathophysiology remains poorly understood.
Sihong Huang, Jungong Han, Hairong Zheng, Mengjun Li, Chuxin Huang, Xiaoyan Kui, Jun Liu   +6 more
doaj   +1 more source

Usability of World Health Organization Disability Assessment Schedule in chronic traumatic brain injury

Journal of Rehabilitation Medicine, 2018
Objectives: To investigate functioning measured with the 12-item World Health Organization Disability Assessment Schedule (WHODAS 2.0) in patients with mild, moderate and severe traumatic brain injury, and to compare patients’ experiences with ...
Sinikka Tarvonen-Schröder, Olli Tenovuo, Anne Kaljonen, Katri Laimi   +3 more
doaj   +1 more source

Journey to the other side of the brain: asymmetry in patients with chronic mild or moderate traumatic brain injury

Concussion, 2023
Aim: Patients with chronic mild or moderate traumatic brain injury have some regions of brain atrophy (including cerebral white matter) but even more regions of abnormal brain enlargement (including other cerebral regions). Hypothesis: Ipsilateral injury
David E Ross, John D Seabaugh, Jan M Seabaugh, Claudia Alvarez, Laura Peyton Ellis, Christopher Powell, Christopher Reese, Leah Cooper, Katherine Shepherd, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
doaj   +1 more source

A cognitive profile of South African children with traumatic brain injury [PDF]

, 2010
Includes bibliographical references (leaves 86-105).Research conducted on pediatric populations have shown that an event such as a traumatic brain injury (TBI) experienced in childhood can lead to persistent neuropsychological deficits months, even years
Malgas, Nancy
core   +1 more source

Diminished supraspinal pain modulation in patients with mild traumatic brain injury

Molecular Pain, 2016
Background Chronic pain conditions are highly prevalent in patients with mild traumatic brain injury. Supraspinal diffuse axonal injury is known to dissociate brain functional connectivity in these patients.
Albert Leung MD, Shivshil Shukla BS, Eric Yang BS, Bryan Canlas BS, Mawj Kadokana BS, Jason Heald BS, Ariea Davani BS, David Song MD, Lisa Lin MD, Greg Polston MD, Alice Tsai DO, Roland Lee MD   +11 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Calcium and Non-Penetrating Traumatic Brain Injury: A Proposal for the Implementation of an Early Therapeutic Treatment for Initial Head Insults

Biomolecules
Finding an effective treatment for traumatic brain injury is challenging for multiple reasons. There are innumerable different causes and resulting levels of damage for both penetrating and non-penetrating traumatic brain injury each of which shows ...
Danton H. O’Day
doaj   +1 more source

Social Competence and Executive Functioning in Adolescents Following a Mild Traumatic Brain Injury [PDF]

, 2014
A traumatic brain injury (TBI) is one of the most common injuries sustained by adolescents and a leading cause of death and long-term disability. The vast majority of these cases are mild and yet they can cause a range of difficulties across multiple ...
Hollands, David Michael
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source