Results 51 to 60 of about 552,659 (305)

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

open access: yesHepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou   +15 more
wiley   +1 more source

Military English Teaching in Chinese Military Academies: A Review

open access: yesJournal of Language Teaching and Research, 2022
Through reviewing studies of military English teaching in the context of Chinese military academies, this paper is aimed at locating both research gaps and weaknesses as well as achievements in an effort to contribute to research and development of military English teaching in Chinese military academies.
Wenjun Zhong, Yuxuan Zhang, Yajing Jin
openaire   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Editorial [PDF]

open access: yes, 1998
The original publication is available at http://scientiamilitaria.journals.ac.za/pubIn September 1998 the Faculty of Military Science, University of Stellenbosch (Military Academy) in association with the Institute for Security Studies hosted a ...
Королева, Анна Анатольевна   +1 more
core  

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

Permanent Military Professor Program [PDF]

open access: yes, 2013
This instruction addresses the PMP and JPMP components. The PMP program was created in 1997 to establish a cadre of career naval officers in the grades of captain and commander, with both doctoral degrees and extensive operational experience, who would ...
Chief of Naval Operations
core  

Realization of a Bilayer Elastic Topological Insulator

open access: yesAdvanced Science, EarlyView.
Bilayer elastic wave topological insulators are experimentally realized, introducing the layer degree of freedom to access four topological phases. This enables diverse domain walls and transmission behaviors, including interlayer conversion and beam splitting.
Chengzhi Ma   +4 more
wiley   +1 more source

INFLUENCE OF THE MOTORIC ABILITIES ON MOTORIC EFFICINCY IN MILITARY ACADEMY STUDENTS [PDF]

open access: yesSport Mont, 2008
Physical education is part of the curriculum at the Military Academy. It is a complex pedagogical in wich physical exercises are used as the primary means and method of achieving the goals which had been set, and fulfilling the contents of the programme.
Lela Marić, Branko Krsmanović
doaj  

Asserting the Portuguese Civil Engineering Identity: the Role Played by the École des ponts et chaussées [PDF]

open access: yes, 2009
This paper focuses on the Portuguese engineers who returned to Portugal following a training period at École des Ponts et Chaussées, in Paris between 1831 and 1870.
Matos, Ana Cardoso de
core  

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