ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages +7 more
wiley +1 more source
Role of Cardoon (<i>Cynara</i> spp.) and Raw Milk Microbiota in Iberian PDO and PGI Small Ruminants' Milk Cheeses. [PDF]
Pereira CD +4 more
europepmc +1 more source
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English +4 more
wiley +1 more source
Boosting Recombinant Bovine Chymosin in <i>Komagataella phaffii</i> via Fusion Protein and Constitutive Promoter Expression. [PDF]
Ren X +8 more
europepmc +1 more source
Abstract During glucose uptake into muscle, GLUT‐4 can translocate with stimulus from insulin or muscle contraction via exercise, but some exercise‐intolerant populations are unable to benefit from improved glycaemic control. We investigated how passive movement training (PMT) and passive movement training with blood flow restriction (PMT+BFR) could be
Jay Railton‐Sowerby +8 more
wiley +1 more source
Longitudinal clinical-chemical profiles and metabolic dynamics in Thuringian Forest dairy goats during pregnancy and lactation under organic farming conditions. [PDF]
Brenner NL +3 more
europepmc +1 more source
Camel Milk Shelf Life Optimization: Physicochemical Deterioration, Bioactive Preservation, and Non-Thermal Technologies: A Narrative Review. [PDF]
Elsahoryi NA, Alhaj OA, Jahrami H.
europepmc +1 more source
Vitamin K Biochemistry and Pharmacokinetics: The Basis of Late Vitamin K Deficiency Intracranial Bleeding in Early Infancy. [PDF]
Perrone S +4 more
europepmc +1 more source
Heterologous Production of Cyprosin B in Nicotiana benthamiana: Unveiling the Role of the Plant-Specific Insert Domain in Protein Function and Subcellular Localisation. [PDF]
Muthusamy S +8 more
europepmc +1 more source

