Results 141 to 150 of about 1,251,485 (312)

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Molecular Appendix Adjusted Architectural Propagations of Red‐Light Controlled Macroscopic Photoactuating Performances

Advanced Robotics Research, EarlyView.
Amphiphilic chloroazobenzenes, bearing different amino acids as end groups alanine, phenylalanine, and valine, exhibit excellent photoisomerizations. Varying structures of three amino acid groups participate in supramolecular formations and therefore photoinduced morphological transformations via adjusting intermolecular interactions. These interaction
Shuangshuang Meng, Ming‐Hin Chau, Takashi Kajitani, Franco King‐Chi Leung   +3 more
wiley   +1 more source

Grounding Large Language Models for Robot Task Planning Using Closed‐Loop State Feedback

Advanced Robotics Research, EarlyView.
BrainBody‐Large Language Model (LLM) introduces a hierarchical, feedback‐driven planning framework where two LLMs coordinate high‐level reasoning and low‐level control for robotic tasks. By grounding decisions in real‐time state feedback, it reduces hallucinations and improves task reliability.
Vineet Bhat, Ali Umut Kaypak, Prashanth Krishnamurthy, Ramesh Karri, Farshad Khorrami   +4 more
wiley   +1 more source

Inactivation of Avian Influenza Virus in Raw Milk Kefir. [PDF]

Food Environ Virol
Porto-Fett ACS, Alvarez-Narvaez S, Vinayamohan PG, Harrell T, Shwani A, Suarez DL, Luchansky JB.   +6 more
europepmc   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

The Circadian Composition of Breast Milk: A Natural Starting Point for Chrononutrition. [PDF]

Curr Nutr Rep
Aksu S, Arslan S.
europepmc   +1 more source

SHEEP | Milk

, 2002
Ramos González, María Mercedes, Juárez, Manuela   +1 more
openaire   +2 more sources

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source