Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao +21 more
wiley +1 more source
Milk Alternatives and Non-Dairy Fermented Products: Trends and Challenges. [PDF]
Pontonio E, Rizzello CG.
europepmc +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source
Predicting Microbial Growth Dynamics in Commercial Cocoa-Flavored Plant-Based Milk Alternatives. [PDF]
Gonçalves Lima CM +4 more
europepmc +1 more source
Most Plant-Based Milk Alternatives in the USDA Branded Food Products Database Do Not Meet Proposed Nutrient Standards or Score Well on Nutrient Density Metrics. [PDF]
Drewnowski A.
europepmc +1 more source
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye +9 more
wiley +1 more source
The rise of plant-based milk alternatives: exploring nutritional, health, and sustainability impacts. [PDF]
Asif N +7 more
europepmc +1 more source
Perspective: Identifying Ultra-Processed Plant-Based Milk Alternatives in the USDA Branded Food Products Database. [PDF]
Drewnowski A.
europepmc +1 more source
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Comprehensive allergen screening and semi-quantification in plant based Milk alternatives by mass spectrometry. [PDF]
McElroy C, Singh M, Corless S, Hopley C.
europepmc +1 more source

