Results 101 to 110 of about 1,591,321 (343)

A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study utilizes patient‐derived osteosarcoma organoids and CRISPR screening to identify ERCC6 and HNRNPM as key mediators of cisplatin resistance via the PI3K/AKT pathway and BAX alternative splicing. These findings provide novel insights and potential therapeutic targets for overcoming chemoresistance in osteosarcoma.
Ruiling Xu   +11 more
wiley   +1 more source

How and why to be human milk donor? A descriptive study

open access: yesOnline Brazilian Journal of Nursing, 2008
<p style="text-align: justify" class="MsoNormal"><span style="font-size: 10pt; font-family: Verdana">It is a research developed at a Human Milk Bank to inquire as the mother givers had become Human Milk (HM) giver of a Human Milk Bank<span&
Cynara Gurgel Pereira   +3 more
doaj   +2 more sources

Articulation between nursing systems and operational procedures: nursing perspectives of milk banks

open access: yesRevista de Enfermagem da Universidade Federal de Santa Maria, 2017
Aim: to understand the articulation facets of Nursing Care Systematization with the regulations used by nurses of the Human Milk Bank. Method: a descriptive study of a qualitative approach, carried out from May to November2014, inthe seven milk banks of ...
Giovanna Rosario Soanno Marchiori   +5 more
doaj   +1 more source

Creating Shared Value in India: How Indian Corporations Are Contributing to Inclusive Growth While Strengthening Their Competitive Advantage [PDF]

open access: yes, 2011
Leading companies are finding new ways to accelerate growth and increase competitive advantage through innovative business models that meet societal needs at scale.
Lalitha Vaidyanathan   +3 more
core  

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

open access: yesAdvanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu   +14 more
wiley   +1 more source

Brazilian network of human milk banks: a network based on trust

open access: yesRECIIS, 2018
This article bases on a study that aimed to identify the existing links in the rBLH-BR – Rede Brasileira de Bancos de Leite Humano (Brazilian Network of Human Milk Banks).
Mariana Simoes Barros   +2 more
doaj  

Fn14 Controls the SIRT2‐Mediated Deacetylation of Slug to Inhibit the Metastasis of Epithelial Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu   +9 more
wiley   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu   +8 more
wiley   +1 more source

The second Italian human milk banks survey

open access: yes, 2019
Background: In the latest decades some compelling evidence confirmed the substantial benefits of using human milk, especially for preterm infants [1-5]. Donor human milk is a valid alternative.
A. Ambruzzi   +9 more
semanticscholar   +1 more source

Mending the Meltdown: Fending off the Interventions and Resurrecting the Market [PDF]

open access: yes
This paper gives an Austrian economics answer to the present world economic crisis. It uses the Austrian Business Cycle Theory to analyze the root causes of this crisis and then presents the real solution of this problem.Austrian Business Cycle Theory ...
Raj, Madhusudan
core   +1 more source

Home - About - Disclaimer - Privacy