Results 81 to 90 of about 1,716,846 (311)

Maintaining human milk bank services throughout the COVID‐19 pandemic: A global response

Maternal and Child Nutrition, 2021
If maternal milk is unavailable, the World Health Organization recommends that the first alternative should be pasteurised donor human milk (DHM). Human milk banks (HMBs) screen and recruit milk donors, and DHM principally feeds very low birth weight ...
Natalie Shenker, Marta Staff, Amy Vickers, Joao Aprigio, Satish Tiwari, Sushma Nangia, Ruchika Chugh Sachdeva, Vanessa Clifford, Anna Coutsoudis, Penny Reimers, Kiersten Israel‐Ballard, Kimberly Mansen, Radmila Mileusnic‐Milenovic, Aleksandra Wesolowska, Johannes B. van Goudoever, Mohammadbagher Hosseini, Daniel Klotz, Anne Hagen Grøvslien, Gillian Weaver, Virtual Collaborative Network of Milk Banks and Associations   +19 more
doaj   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Food Access in Petersburg, Virginia: Final Report and Recommendations [PDF]

, 2019
The City of Petersburg has long suffered with issues of limited access to food and food insecurity. Food deserts, or areas underserved by retail food options, are prevalent throughout the City.
Ashby, Logan, De Leon, Chesley, Mitchell, Shekinah, Nixon-Garrison, Michael, Pino-Mareno, Gabriella, Roderick, Elizabeth, Smith, Jeff, URSP 666 (Commercial Revitalization)   +7 more
core   +1 more source

Optimal distribution and utilization of donated human breast milk: a novel approach [PDF]

, 2016
Background: The nutritional content of donated expressed breast milk (DEBM) is variable. Using DEBM to provide for the energy requirements of neonates is challenging.
Barnett, Debbie, Cairns, Lorraine, Cooper, Andrew, Gentles, Emma, Gerasimidis, Konstantinos, McKerracher, Lorna, Simpson, Judith H.   +6 more
core   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

How and why to be human milk donor? A descriptive study

Online Brazilian Journal of Nursing, 2008
It is a research developed at a Human Milk Bank to inquire as the mother givers had become Human Milk (HM) giver of a Human Milk Bank(HMB). To identify, according to these, which the reasons that had stimulated them to be givers.Qualitative research ...
Cynara Gurgel Pereira, Maria Vera Lúcia Moreira Leitão cardoso, Grazielle Roberta Freitas da Silva, Maria Gorette Andrade Bezerra   +3 more
doaj   +2 more sources

Representations of women milk donors on donations for the human milk bank

Cadernos de Saúde Coletiva, 2016
Human milk banks (HMBs) have difficulty maintaining and increasing their stocks, and the number of women enrolling as members remains low. The present qualitative study, based on social representation theory, aimed to understand women’s representations ...
Wanessa Debôrtoli de Miranda, Maria Cristina Passos, Maria Imaculada de Fátima Freitas, Palmira de Fátima Bonolo   +3 more
doaj   +1 more source