Results 111 to 120 of about 1,591,321 (343)

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

Advanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang, Wanming Li, Yuqiong Lv, Wei Ba, Ying Jiang, Xiaoshuai Li, Jin Fang   +6 more
wiley   +1 more source

Maternal insecurity in breastfeeding women served at a human milk bank [PDF]

, 2021
Waleska Lima Alves Simas, Jaíza Sousa Penha, Liane Batista da Cruz Soares, Poliana Pereira Costa Rabêlo, Bruno Luciano Carneiro Alves de Oliveira, Feliciana Santos Pinheiro   +5 more
openalex   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

The dialog between health and foreign policy in Brazilian cooperation in human milk banks.

Ciência & Saúde Coletiva, 2017
Mother's milk is the primary source of nourishment in early infancy. When this source is unavailable, secondary sources may be used, such as human milk banks. The first milk bank in Brazil was created in 1943, and they have been used ever since.
Tiago Mocellin Pittas, C. Dri
semanticscholar   +1 more source

Human Milk Banking-Facts and Issues to Resolve [PDF]

, 2010
The number of human milk banks is increasing worldwide. Although the beneficial effects of feeding premature infants with their mother’s milk are well documented, less is known about the effects of feeding these infants with pasteurized donor milk.
Agostoni, Bjorksten, de Silva, Ehrenkranz, Flacking, Hamprecht, Hylander, I. Caroline Kruger, Ineke Van Vliet, Johannes B. Van Goudoever, Lucas, Marijn J. Vermeulen, Narayanan, Orloff, Quigley, Richardus, Singhal, Singhal, Terpstra, Tully, Vetrugno, Willemijn E. Corpeleijn   +21 more
core   +5 more sources

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source

Random Reflections on a Human Milk Bank [PDF]

, 1951
J. G. Wilson
openalex   +1 more source

ENHANCED METHOD FOR AMPLIFYING ANTIMICROBIAL ACTIVITY OF LACTOPEROXIDASE SYSTEM IN MILK AND DERIVED PRODUCTS BY CARROT EXTRACT AND BETA CAROTENE [PDF]

, 2014
OSCN–  has  been  known  and  well  documented  as  natural  antimicrobial  agent    generated  from the  lactoperoxidase  system (LPOS)  but  the  antimicrobial  activity  exerted  from  this  system  is  too  low  for  certain  food  such  as  milk ...
AL-BAARRI, Ahmad N, LEGOWO, Anang M
core  

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

EFFECT OF BANKED HUMAN BREAST MILK(BHBM) ON THE POST-NATAL EVOLUTION OF MIDARM CIRCUMFERENCE (MAC), TRICIPITAL (T), AND SUBSCAPULAR(S) SKINFOLD (SKF)THICKNESS, ARM MUSCLE(AMA) AND FAT AREAS (AFA) IN APPROPRIATE(AGA) AND SMALL FOR GESTATIONAL AGE(SGA) VERY LOW BIRTH-WEIGHT INFANTS (VLBW) [PDF]

, 1984
Jean‐Louis Excler, L Sann, Y Lasne, J Picard   +3 more
openalex   +1 more source