Results 201 to 210 of about 586,800 (361)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Reproductive Performance and Milk Composition of Sows Fed Diets Supplemented with an Immunomodulator. [PDF]

open access: yesAnimals (Basel)
Estienne MJ   +5 more
europepmc   +1 more source

Effect of gestational age (preterm or full term) on lipid composition of the milk fat globule and its membrane in human colostrum [PDF]

open access: green, 2020
Antonio Pérez‐Gálvez   +5 more
openalex   +1 more source

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

open access: yesAdvanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun   +12 more
wiley   +1 more source

Effects of Dietary Chromium Supplementation During Late Lactation on Productive Performance, Milk Composition, and Immune and Antioxidant Responses in Dairy Cows. [PDF]

open access: yesAnimals (Basel)
Turcatto N   +8 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Creation of Machine Learning Models Trained on Multimodal Physiological, Behavioural, Blood Biochemical, and Milk Composition Parameters for the Identification of Lameness in Dairy Cows. [PDF]

open access: yesBiosensors (Basel)
Džermeikaitė K   +8 more
europepmc   +1 more source

<b>Intake, digestibility of nutrients, milk production and composition in dairy cows fed on diets containing cashew nut shell liquid [PDF]

open access: diamond, 2014
Diogo Antignani Coutinho   +5 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

open access: yesAdvanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu   +12 more
wiley   +1 more source

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