Results 81 to 90 of about 7,235,853 (411)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Amino acids and mammary gland development: nutritional implications for milk production and neonatal growth

Journal of Animal Science and Biotechnology, 2016
Milk is synthesized by mammary epithelial cells of lactating mammals. The synthetic capacity of the mammary gland depends largely on the number and efficiency of functional mammary epithelial cells.
R. Rezaei, Zhenlong Wu, Yongqing Hou, F. Bazer, Guoyao Wu   +4 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Effects of L-citrulline Supplementation on the Athletic Performance, Physiological and Biochemical Parameters, Antioxidant Capacity, and Blood Amino Acid and Polyamine Levels in Speed-Racing Yili Horses

Animals
The objective of this study was to evaluate the effects of pre-exercise L-citrulline supplementation on the athletic performance of Yili speed-racing horses during a high-intensity exercise. On the 20th day of the experiment, blood samples were collected
Peiyao Li, Shuo Sun, Wenjie Zhang, Wen Ouyang, Xiaobin Li, Kailun Yang   +5 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Investigation on Fermented Milk Quality after the Addition of Flaxseed Mucilage and the Use of Lactobacillus delbrueckii subsp. bulgaricus and Lactiplantibacillus plantarum AG9

Frontiers in Bioscience-Elite
Background: Flaxseed mucilage (FSM) is one of the healthy components of flaxseed. FSM is an example of a material that can be used in the food, cosmetic, and pharmaceutical industries due to its rheological properties.
Alya Sungatullina, Tatyana Petrova, Elena Nikitina   +2 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Milk and milk products

, 2018
Milk is a nutritious food that plays an important role in the diet of particular groups, such as the new-born, children, the elderly and pregnant women. In addition to those groups, milk is consumed worldwide by a large part of the population, either alone or in the form of dairy products.
Joana S. Amaral, Isabel Mafra, Audrey Pissard, Juan Antonio Fernández Pierna, Vincent Baeten   +4 more
openaire   +3 more sources

Reproductive Management of Dairy Cows with Particular Reference to Organic Systems [PDF]

, 2008
Reproductive efficiency is a major factor affecting production and economic efficiency indairy herds. In seasonally calving herds the requirement of good reproductive performance is of greater importance than in other production systems in order to ...
Diskin, Michel G., Kelly, Frank
core  

Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows.

Journal of Dairy Science, 2019
Greenhouse gases originating from the dairy sector, including methane (CH4), contribute to global warming. A possible strategy to reduce CH4 production is to use genetic selection. This requires genetic parameters for CH4 production and correlations with
I. Breider, E. Wall, P. Garnsworthy
semanticscholar   +1 more source