Results 51 to 60 of about 145,586 (292)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Deciphering the Kinematic Substructure of Local Dark Matter with LAMOST K Giants
The Astrophysical JournalNumerical simulations indicate that correlations exist between the velocity distributions of stars and dark matter (DM). We study the local DM velocity distribution based on these correlations.
Hai Zhu +7 more
doaj +1 more source
Mass Models of the Milky Way and Estimation of Its Mass from the Gaia DR3 Data Set
The Astrophysical Journal, 2023 We use data from the Gaia DR3 data set to estimate the mass of the Milky Way (MW) by analyzing the rotation curve in the range of distances 5 to 28 kpc. We consider three mass models: The first model adds a spherical dark matter (DM) halo, following the ...
Francesco Sylos Labini +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 2007 The Milky Way is the only galaxy for which we can resolve individual stars at all evolutionary phases, from the Galactic center to the outskirt. The last decade, thanks to the advent of near IR detectors and 8 meter class telescopes, has seen a great ...
Alard +15 more
core +1 more source
Dust Emissivity Variations In the Milky Way [PDF]
, 2009 Dust properties appear to vary according to the environment in which the dust evolves. Previous observational indications of these variations in the FIR and submm spectral range are scarce and limited to specific regions of the sky.
Abergel +43 more
core +3 more sources
Nature, 1870 YOUR correspondent, Mr. Jeremiah, after quoting the words of the Llangadock “Oracle,” adds, “meaning that the wind will blow from that quarter.” Did Mr. Jeremiah interpret the man's meaning correctly? If so it is at variance with a popular belief in Hampshire, viz., that in whichever way the Milky Way may be seen over night, the wind is sure to blow ...
openaire +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
HI shells in the outer Milky Way
, 2005 We present results of a method for an automatic search for HI shells in 3D data cubes and apply it to the Leiden-Dwingeloo HI survey of the northern Milky Way.
Ehlerova, S., Palous, J.
core +1 more source
The origin of the Milky Way globular clusters [PDF]
, 2016 We present a cosmological zoom-in simulation of a Milky Way-like galaxy used to explore the formation and evolution of star clusters. We investigate in particular the origin of the bimodality observed in the colour and metallicity of globular clusters ...
Agertz, Oscar +2 more
core +2 more sources