Results 151 to 160 of about 44,865 (311)
The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease
Brain Pathology, EarlyView.SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery +17 more
wiley +1 more source
Cell Proliferation, EarlyView.Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie +6 more
wiley +1 more source
The evolution of stellar metallicity gradients of the Milky Way disk from LSS-GAC main sequence turn-off stars: a two-phase disk formation history? [PDF]
, 2015 Maosheng Xiang +10 more
openalex +1 more source
Asymmetric Drift Map of the Milky Way disk Populations between 8$-$16 kpc with LAMOST and Gaia datasets [PDF]
, 2023 Xin Li +6 more
openalex +1 more source
Cell Proliferation, EarlyView.Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu +4 more
wiley +1 more source
Rising from the Ashes: A Metallicity-dependent Star Formation Gap Splits the Milky Way’s α Sequences
The Astrophysical JournalThe elemental abundance distribution of stars encodes the history of the gas-phase abundance in the Milky Way. Without a large, unbiased sample of highly precise stellar ages, the exact timing and nature of this history must be inferred from the ...
Angus Beane
doaj +1 more source
The formation and survival of the Milky Way’s oldest stellar disk
Nature AstronomyPublished in Nature Astronomy on 10 October, 2024; This manuscript is the accepted ...
Maosheng Xiang +5 more
openaire +2 more sources
Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism
Cell Proliferation, EarlyView.Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang +11 more
wiley +1 more source
The Astrophysical Journal LettersStellar mass is the most fundamental property of a galaxy. While it has been robustly measured for millions of external galaxies, it remains poorly constrained for the Milky Way because of the strong selection effect from our inside perspective.
Jianhui Lian +4 more
doaj +1 more source
The age-kinematical features in the Milky Way outer disk [PDF]
, 2016 Chao Liu, Hai-Jun Tian, Jun-Chen Wan
openalex +1 more source