Results 101 to 110 of about 179,998 (300)

The Milky Way satellite galaxy Leo T: A perturbed cored dwarf [PDF]

Astronomy & Astrophysics
The impact of the dynamical state of gas-rich satellite galaxies at the early moments of their infall into their host systems and the relation to their quenching process are not completely understood at the low-mass regime.
M. Blaña, A. Burkert, M. Fellhauer, D. Calderón, M. Behrendt, M. Schartmann   +5 more
semanticscholar   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

The Milky Way atlas for linear filaments II. clump rotation versus filament orientation [PDF]

Monthly notices of the Royal Astronomical Society
Dense clumps distributed along filaments are the immediate medium for star formation. Kinematic properties of the clumps, such as velocity gradient and angular momentum, combined with filament orientation, provide important clues to the formation ...
Xue-Fang Xu, Ke Wang, Q. Gou, T. Baug, Di Li, Chun-Pu Duan, Juncheng Lei   +6 more
semanticscholar   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

HR-GO. II. Chemical Abundances of Low-E Retrograde Dynamically Tagged Groups: Revealing Thamnos as a Very Metal-poor Substructure

The Astrophysical Journal
Milky Way halo substructures identified in dynamical space are known to suffer from contamination from the Milky Way in situ stars, which makes their accreted origins uncertain. We present detailed chemical abundances of 35 stars belonging to two sets of
Renjing Xie, Zhen Yuan, Haining Li, Tadafumi Matsuno, Nicolas F. Martin, Ruizhi Zhang, Zhiqiang Yan, Federico Sestito, Guillaume F. Thomas, Projjwal Banerjee, Ruizheng Jiang, Linda Lombardo, David S. Aguado, Kohei Hattori, Gang Zhao   +14 more
doaj   +1 more source

The baryonic mass estimates of the Milky Way halo in the form of high-velocity clouds [PDF]

New Astronomy
The halo of our Galaxy is populated with a significant number of high-velocity clouds (HVCs) moving with a speed up to $500$ km/s. It is suggested that these HVCs might contain a non-negligible fraction of the missing baryons. The main aim of the current
N. Tahir, Martin Lopez Corredoira, F. De Paolis   +2 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars

The Astrophysical Journal Supplement Series
A detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun, Han Shen, Biwei Jiang, Xiaowei Liu   +3 more
doaj   +1 more source

Large-scale Gas Dynamics in the Milky Way

, 2003
We present new gas flow models for the Milky Way inside the solar circle. Using a mass model derived from the COBE/DIRBE maps and clump giant star counts, and using a parametric model for the spiral arm pattern in the disk, we calculate the gas flow and compare with 12CO observations.
Englmaier, P., Gerhard, O. E., Bissantz, N.   +2 more
openaire   +2 more sources

Gradient‐Conductivity Architecture Enables Synchronous Enhancement of Sensitivity and Detection Range in Multifunctional All‐Paper Sensors

Advanced Functional Materials, EarlyView.
A gradient‐engineered all‐paper sensor is fabricated by integrating MXene and in situ grown AgNPs within hierarchical cellulose networks. The device breaks the sensitivity–detection range trade‐off through cascaded conductive pathways, enabling ultrahigh pressure sensitivity, humidity–pressure decoupled dual‐mode sensing, and outstanding EMI shielding,
Ao Li, Jun Xu, Dezhong Xu, Zhaohui Zhang, Jiyi Li, Daxian Cao, Kefu Chen, Mizi Fan   +7 more
wiley   +1 more source