Results 151 to 160 of about 7,795,018 (296)

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Where is the Supervirial Gas? The Supply from Hot Inflows

The Astrophysical Journal
To understand the presence of the supervirial temperature gas detected in the Milky Way (MW), we present our findings from isolated galaxy simulations of MW-mass systems using GIZMO with the Feedback in Realistic Environments (FIRE-2) stellar feedback ...
Manami Roy, Kung-Yi Su, Smita Mathur, Jonathan Stern   +3 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Differential Accretion of Ionized Low-velocity Gas at the Milky Way’s Disk–Halo Interface

The Astrophysical Journal
We measure line-of-sight velocities of metal absorption and H I emission along 132 QSO sight lines in order to study gas accretion and outflow at the disk–halo interface of the Milky Way.
Hannah V. Bish, Jessica K. Werk, J.E.G. Peek, Enrico Di Teodoro, Yong Zheng, Mary Putman   +5 more
doaj   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

The Milky Way Radial Metallicity Gradient as an Equilibrium Phenomenon: Why Old Stars Are Metal Rich

The Astrophysical Journal
Metallicities of both gas and stars decline toward large radii in spiral galaxies, a trend known as the radial metallicity gradient. We quantify the evolution of the metallicity gradient in the Milky Way as traced by APOGEE red giants with age estimates ...
James W. Johnson, David H. Weinberg, Guillermo A. Blanc, Ana Bonaca, Gwen C. Rudie, Yuxi (Lucy) Lu, Bronwyn Reichardt Chu, Emily J. Griffith, Tawny Sit, Jennifer A. Johnson, Liam O. Dubay, Miqaela K. Weller, Daniel A. Boyea, Jonathan C. Bird   +13 more
doaj   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

True Pair-instability Supernova Descendant: Implications for the First Stars’ Mass Distribution

The Astrophysical Journal Letters
The initial mass function (IMF) of the first Population III (Pop III) stars remains a persistent mystery. Their predicted massive nature implies the existence of stars exploding as pair-instability supernovae (PISNe), but no observational evidence had ...
Ioanna Koutsouridou, Stefania Salvadori, Ása Skúladóttir   +2 more
doaj   +1 more source

Keratin–Melanin Complexation Enables Robust, Delamination‐Resistant Feather‐Inspired Structural Color Coatings for Flexible and Curved Substrates

Advanced Materials Interfaces, EarlyView.
Providing mechanically robust structural color coating technology inspired by cooperative interactions in nature. The spatial arrangement of melanin particles within the keratin matrix generates angle‐independent structural colors. Diverse functional groups in keratin and melanin contribute to interparticle and substrate adhesion, resulting in the ...
Taisei Harada, Yui Maejima, Ryota Iwamori, Hideyuki Mitomo, Hirotoshi Tamayama, Shin‐ichi Takeda, Daisuke Unabara, Tasuku Hamaguchi, Koji Yonekura, Gen Morimoto, Hiroshi Fudouzi, Keiki Kishikawa, Michinari Kohri   +12 more
wiley   +1 more source

A North–South Metallicity Asymmetry in the Outer Galactic Disk—Evidence for the Pericentric Passage of the Sagittarius Dwarf Galaxy

The Astrophysical Journal Letters
We present maps of the mean metallicity distributions on the Galactocentric R – Z plane at different azimuthal angles using red clump stars selected from the LAMOST and APOGEE surveys.
Chun Wang, Yang Huang, Timothy C. Beers, Payel Das, Haibo Yuan, Lizhi Xie, Shi Shao   +6 more
doaj   +1 more source