Results 141 to 150 of about 7,795,018 (296)

Mapping the Galactic Disk with the LAMOST and Gaia Red Clump Sample. VIII. Mapping the Kinematics of the Galactic Disk Using Mono-age and Mono-abundance Stellar Populations

open access: yesThe Astrophysical Journal
We present a comprehensive study of the kinematic properties of the different Galactic disk populations, as defined by the chemical abundance ratios and stellar ages, across a large disk volume (4.5 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc), by using the ...
Weixiang Sun   +7 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Radial Wave in the Galactic Disk: New Clues to Discriminate Different Perturbations

open access: yesThe Astrophysical Journal
Decoding the key dynamical processes that shape the Galactic disk structure is crucial for reconstructing the Milky Way’s evolution history. The second Gaia data release unveils a novel wave pattern in the L _Z −〈 V _R 〉 space, but its formation ...
Chengye Cao   +3 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

The Low-α Splash Population in the Milky Way

open access: yesThe Astrophysical Journal Letters
The Milky Way metal-rich halo-like component, also known as the Splash, consists of old (age > 10 Gyr), metal-rich ([Fe/H] > −0.7), high- α stars, i.e., thick-disk-like chemistry, on halo-like orbits (eccentricity > 0.6).
Lais Borbolato   +7 more
doaj   +1 more source

Milky Way evolution on a human timescale

open access: yes
How do galaxies form and evolve? This is one of the most puzzling questions in astronomy. Galaxy assembly takes place throughout the entire history of the Universe, but our understanding of it is hampered by the unfortunate fact that we can only observe galaxies at a single moment in time.
Eugene, Neige
openaire   +2 more sources

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

open access: yesAdvanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han   +4 more
wiley   +1 more source

The Milky Way and the evolution of disk galaxies

open access: yes, 2002
We present a phenomenological approach to the study of disk galaxy evolution, based on i) a detailed modelling of the Milky Way (used as a prototype disk galaxy) and ii) an extension of the model to other disks through some simple scaling relations, obtained in the framework of Cold Dark matter models.
openaire   +2 more sources

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

On the early chemical evolution of the Milky Way

open access: yes, 2006
A few topics concerning the early chemical evolution of the Milky Way are critically discussed. In particular, it is argued that: 1) Observed abundance patterns of extremely metal poor stars (of Pop. II) do not constrain the mass range of the first generation (Pop.
openaire   +2 more sources

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